Sulfur trioxide

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Names

[ CAS No. ]:
7446-11-9

[ Name ]:
Sulfur trioxide

[Synonym ]:
Schwefeltrioxid
MFCD00011452
SULPHUR TRIOXIDE
Sulfan
Sulfur oxide (SO3)
Sulfuric oxide
SULFAN(R)
sulfuric acid anhydride
SO3
EINECS 231-197-3
Sulfur trioxide
SULFURIC ANHYDRIDE
sulfur(VI) oxide

Chemical & Physical Properties

[ Density]:
1.97 g/mL at 25 °C(lit.)

[ Boiling Point ]:
44.8 °C

[ Melting Point ]:
16.8 °C(lit.)

[ Molecular Formula ]:
O3S

[ Molecular Weight ]:
80.06320

[ Exact Mass ]:
79.95680

[ PSA ]:
83.30000

[ LogP ]:
0.29180

[ Vapour density ]:
2.8 (vs air)

[ Vapour Pressure ]:
280 mm Hg ( 25 °C)

[ Stability ]:
Stable. Incompatible with organic materials, finely powdered metals, bases, water, cyanides and a wide variety of other chemicals. Reacts violently with water, oxygen and other chemicals - read a full data sheet before use.

[ Water Solubility ]:
reacts violently

MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
WT4830000
CHEMICAL NAME :
Sulfur trioxide
CAS REGISTRY NUMBER :
7446-11-9
LAST UPDATED :
199710
DATA ITEMS CITED :
13
MOLECULAR FORMULA :
O3-S
MOLECULAR WEIGHT :
80.06
WISWESSER LINE NOTATION :
S O3

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
TCLo - Lowest published toxic concentration
ROUTE OF EXPOSURE :
Inhalation
SPECIES OBSERVED :
Human
DOSE/DURATION :
30 mg/m3
TOXIC EFFECTS :
Sense Organs and Special Senses (Olfaction) - effect, not otherwise specified Lungs, Thorax, or Respiration - cough Lungs, Thorax, or Respiration - other changes
REFERENCE :
JPBAA7 Journal of Pathology and Bacteriology. (London, UK) V.1-96, 1892-1968. For publisher information, see JPTLAS. Volume(issue)/page/year: 68,197,1954
TYPE OF TEST :
LCLo - Lowest published lethal concentration
ROUTE OF EXPOSURE :
Inhalation
SPECIES OBSERVED :
Rodent - guinea pig
DOSE/DURATION :
30 mg/m3/6H
TOXIC EFFECTS :
Liver - hepatitis (hepatocellular necrosis), diffuse Lungs, Thorax, or Respiration - structural or functional change in trachea or bronchi Endocrine - other changes
REFERENCE :
JPBAA7 Journal of Pathology and Bacteriology. (London, UK) V.1-96, 1892-1968. For publisher information, see JPTLAS. Volume(issue)/page/year: 68,197,1954 *** REVIEWS *** IARC Cancer Review:Human Sufficient Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 54,41,1992 IARC Cancer Review:Group 1 IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 54,41,1992 TOXICOLOGY REVIEW AEHLAU Archives of Environmental Health. (Heldref Pub., 4000 Albemarle St., NW, Washington, DC 20016) V.1- 1960- Volume(issue)/page/year: 16,903,1968 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-FINLAND:STEL 1 ppm (3 mg/m3);Skin JAN 1993 OEL-HUNGARY:STEL 1 mg/m3 JAN 1993 OEL-POLAND:TWA 1 mg/m3 JAN 1993 OEL-RUSSIA:STEL 1 mg/m3;Skin JAN 1993 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - M0745 No. of Facilities: 1316 (estimated) No. of Industries: 20 No. of Occupations: 39 No. of Employees: 51404 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - M0745 No. of Facilities: 2524 (estimated) No. of Industries: 17 No. of Occupations: 27 No. of Employees: 56102 (estimated) No. of Female Employees: 3077 (estimated)

Safety Information

[ Symbol ]:

GHS05, GHS07

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H314-H335

[ Supplemental HS ]:
Reacts violently with water.

[ Precautionary Statements ]:
P261-P280-P305 + P351 + P338-P310

[ Personal Protective Equipment ]:
Faceshields;full-face respirator (US);Gloves;Goggles;multi-purpose combination respirator cartridge (US)

[ Hazard Codes ]:
C:Corrosive;

[ Risk Phrases ]:
R14;R34

[ Safety Phrases ]:
S53-S17-S26-S36/37/39-S45-S8-S25

[ RIDADR ]:
UN 1829 8/PG 1

[ WGK Germany ]:
1

[ RTECS ]:
WT4830000

[ Packaging Group ]:
I

[ Hazard Class ]:
8

Synthetic Route

Precursor & DownStream

Precursor

  • oxygen
  • Sulfur
  • SULFUR DIOXIDE
  • carbon monoxide
  • Methanol
  • Selenium oxydichloride
  • Sulfuric acid
  • pyrosulfuryl chloride
  • disulfur dioxide
  • ozone

DownStream

  • Stannane, dichlorobis[(chlorosulfonyl)oxy]
  • methoxysulfonyl methyl sulfate
  • Formaldehyde
  • Ammonia
  • ch3cho
  • methylamine
  • 3,4,5-TRIMETHYLPHENOL
  • 2,3,5-Trimethylphenol
  • 4,4'-Sulfonyldiphenol
  • 2,4-BPS

Articles

Comparative study on intestinal metabolism and absorption in vivo of ginsenosides in sulphur-fumigated and non-fumigated ginseng by ultra performance liquid chromatography quadruple time-of-flight mass spectrometry based chemical profiling approach.

Drug Test. Anal. 7(4) , 320-30, (2015)

Our previous study indicated that sulphur-fumigation of ginseng in post-harvest handling processes could induce chemical transformation of ginsenosides to generate multiple ginsenoside sulphur derivat...

Preparation and in vitro antioxidant activities of 6-amino-6-deoxychitosan and its sulfonated derivatives.

Biopolymers 103 , 539-49, (2015)

The 6-amino-6-deoxychitosan (NC) and their 2, 6-di-N-sulfonated derivatives were prepared via N-phthaloylation, tosylation, azidation, hydrazinolysis, reduction of azide groups and N-sulfonation, and ...

Ligand regulation of a constitutively dimeric EGF receptor.

Nat. Commun. 6 , 7380, (2015)

Ligand-induced receptor dimerization has traditionally been viewed as the key event in transmembrane signalling by epidermal growth factor receptors (EGFRs). Here we show that the Caenorhabditis elega...


More Articles


Related Compounds

  • sulfur trioxide
  • sulfur trioxide
  • sulfur trioxide
  • Sulfur trioxide pyri
  • DMF-sulfur trioxide complex
  • TRIMETHYLAMINESULFUR TRIOXIDE
  • 3-fluoro-N-(2-(1-methyl-1H-pyrrol-2-yl)-2-(4-methylpiperazin-1-yl)ethyl)benzamide
  • 3,4-dichloro-N-(2-(1-methyl-1H-pyrrol-2-yl)-2-(4-methylpiperazin-1-yl)ethyl)benzamide
  • N-(2-(1-methyl-1H-pyrrol-2-yl)-2-(4-methylpiperazin-1-yl)ethyl)benzo[d][1,3]dioxole-5-carboxamide
  • 3-fluoro-4-methoxy-N-(2-(1-methyl-1H-pyrrol-2-yl)-2-(pyrrolidin-1-yl)ethyl)benzenesulfonamide
  • 5-chloro-2-methoxy-N-(2-(1-methyl-1H-pyrrol-2-yl)-2-(pyrrolidin-1-yl)ethyl)benzenesulfonamide
  • N-(2-(3,4-dihydroisoquinolin-2(1H)-yl)-2-(1-methyl-1H-pyrrol-2-yl)ethyl)-4-ethoxybenzenesulfonamide
  • N-(2-(3,4-dihydroisoquinolin-2(1H)-yl)-2-(1-methyl-1H-pyrrol-2-yl)ethyl)-1-phenylmethanesulfonamide
  • 2,5-difluoro-N-(2-(1-methyl-1H-pyrrol-2-yl)-2-morpholinoethyl)benzenesulfonamide
  • 3-chloro-N-(2-(1-methyl-1H-pyrrol-2-yl)-2-morpholinoethyl)benzenesulfonamide
  • 2-chloro-N-(2-(1-methyl-1H-pyrrol-2-yl)-2-morpholinoethyl)benzenesulfonamide
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