α-Dendrotoxin

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Names

[ CAS No. ]:
74504-53-3

[ Name ]:
α-Dendrotoxin

Chemical & Physical Properties

[ Storage condition ]:
−20°C

Safety Information

[ Symbol ]:

GHS06

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H300

[ Precautionary Statements ]:
P264-P301 + P310

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges

[ Hazard Codes ]:
T+

[ Risk Phrases ]:
28

[ Safety Phrases ]:
28-36/37-45

[ RIDADR ]:
UN 2811 6.1/PG 1

[ WGK Germany ]:
3

Articles

Modulation by K+ channels of action potential-evoked intracellular Ca2+ concentration rises in rat cerebellar basket cell axons.

J. Physiol. 520 , 65, (1999)

1. Action potential-evoked [Ca2+]i rises in basket cell axons of rat cerebellar slices were studied using two-photon laser scanning microscopy and whole-cell recording, to identify the K+ channels con...

Delineation of the functional site of alpha-dendrotoxin. The functional topographies of dendrotoxins are different but share a conserved core with those of other Kv1 potassium channel-blocking toxins.

J. Biol. Chem. 273 , 25393, (1998)

We identified the residues that are important for the binding of alpha-dendrotoxin (alphaDTX) to Kv1 potassium channels on rat brain synaptosomal membranes, using a mutational approach based on site-d...

Heterogeneous expression of voltage-gated potassium channels of the shaker family (Kv1) in oligodendrocyte progenitors.

Brain Res. 843 , 145, (1999)

Outwardly rectifying K(+) channels determine the membrane conductance and influence the proliferation rate of glial progenitor cells. To analyze the molecular identity and the functional role of K(+) ...


More Articles

Related Compounds

  • α-Dendrotoxin
  • α-(3,4-Dimethoxyphenyl)-4-[(3,4-dimethoxyphenyl)methyl]tetrahydro-3-hydroxyfuran-3-methanol
  • α-((N-(2-aminobenzyl)-N-methylamino)methyl)-3,4-dimethoxybenzyl alcohol
  • α-(((2-nitrobenzylidene)amino)methyl)-3,4-dimethoxybenzyl alcohol
  • α,3-Bis(acetyloxy)-5-methoxybenzeneacetic acid methyl ester
  • α-(1-Hydroxyethyl)benzenessigsaeure-methylester
  • 2-[1-(2-Methoxybenzenesulfonyl)piperidin-4-yl]-1,8-naphthyridine
  • 2-[1-(3,5-Difluorobenzenesulfonyl)piperidin-4-yl]-1,8-naphthyridine
  • 2-(3,4-Dimethoxyphenyl)-1-(5-{[1,2,4]triazolo[4,3-b]pyridazin-6-yl}-octahydropyrrolo[3,4-c]pyrrol-2-yl)ethan-1-one
  • N-benzyl-5-(9-methyl-9H-purin-6-yl)-octahydropyrrolo[3,4-c]pyrrole-2-carboxamide
  • N-(2,3-dimethoxyphenyl)-4-(1,8-naphthyridin-2-yl)piperidine-1-carboxamide
  • 3-(3a-{[(5-methylpyrimidin-2-yl)oxy]methyl}-octahydrocyclopenta[c]pyrrole-2-carbonyl)-6-(3,5-dimethyl-1H-pyrazol-1-yl)pyridazine
  • 2-(Benzenesulfonyl)-5-{[1,2,4]triazolo[4,3-b]pyridazin-6-yl}-octahydropyrrolo[3,4-c]pyrrole
  • 5-(2-amino-5-methylphenyl)-N-(2,2,2-trifluoroethyl)pyrimidin-2-amine
  • 2-methyl-3-[4-(7-methyl-7H-purin-6-yl)piperazin-1-yl]quinoxaline
  • 3-{5-[9-(2-methoxyethyl)-9H-purin-6-yl]-octahydropyrrolo[3,4-c]pyrrole-2-carbonyl}benzonitrile
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