UBP 302

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Names

[ CAS No. ]:
745055-91-8

[ Name ]:
UBP 302

[Synonym ]:
Tocris-2079
UBC
(S)-1-(2-AMINO-2-CARBOXYETHYL)-3-(2-CARBOXYBENZYL)PYRIMIDINE-2,4-DIONE
UBP-302
2f35

Chemical & Physical Properties

[ Molecular Formula ]:
C15H15N3O6

[ Molecular Weight ]:
333.29600

[ Exact Mass ]:
333.09600

[ PSA ]:
144.62000

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302

[ RIDADR ]:
NONH for all modes of transport

Articles

The limitations of diazepam as a treatment for nerve agent-induced seizures and neuropathology in rats: comparison with UBP302.

J. Pharmacol. Exp. Ther. 351(2) , 359-72, (2014)

Exposure to nerve agents induces prolonged status epilepticus (SE), causing brain damage or death. Diazepam (DZP) is the current US Food and Drug Administration-approved drug for the cessation of nerv...

High-Throughput Screen of GluK1 Receptor Identifies Selective Inhibitors with a Variety of Kinetic Profiles Using Fluorescence and Electrophysiology Assays.

J. Biomol. Screen. 20 , 708-19, (2015)

GluK1, a kainate subtype of ionotropic glutamate receptors, exhibits an expression pattern in the CNS consistent with involvement in pain processing and migraine. Antagonists of GluK1 have been shown ...

A rat model of nerve agent exposure applicable to the pediatric population: The anticonvulsant efficacies of atropine and GluK1 antagonists.

Toxicol. Appl. Pharmacol. 284 , 204-16, (2015)

Inhibition of acetylcholinesterase (AChE) after nerve agent exposure induces status epilepticus (SE), which causes brain damage or death. The development of countermeasures appropriate for the pediatr...


More Articles

Related Compounds

  • UBP 296
  • UBP 282
  • UBP 310
  • Imidazolium compounds, 1-(2-carboxyethyl)-4,5-dihydro-3-(hydroxyethyl)-2-norcoco alkyl, hydroxides, monosodium salts
  • Imidazolium compounds, 1-(2-carboxyethyl)-4,5-dihydro-3-(hydroxyethyl)-2-norcoco alkyl, hydroxides, inner salts
  • 1-Propanaminium, 3,3'-iminobis[N-(carboxymethyl)-N,N-bis(2-hydroxyethyl)-, N-coco alkyl derivs., dihydroxides, bis(inner salts)
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  • (1S,2R)-2-phenylmethoxycarbonylcyclobutane-1-carboxylate
  • (1R)-1-(Trimethylsilyl)hexan-1-OL
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