o-ANISIC ACID, HYDRAZIDE

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Names

[ CAS No. ]:
7466-54-8

[ Name ]:
o-ANISIC ACID, HYDRAZIDE

[Synonym ]:
EINECS 231-260-5
MFCD00014755
2-methoxybenzohydrazide

Chemical & Physical Properties

[ Density]:
1.178g/cm3

[ Melting Point ]:
78-80°C

[ Molecular Formula ]:
C8H10N2O2

[ Molecular Weight ]:
166.17700

[ Exact Mass ]:
166.07400

[ PSA ]:
64.35000

[ LogP ]:
1.38990

[ Index of Refraction ]:
1.558

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
BZ4700000
CHEMICAL NAME :
o-Anisic acid, hydrazide
CAS REGISTRY NUMBER :
7466-54-8
BEILSTEIN REFERENCE NO. :
2208367
LAST UPDATED :
199612
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C8-H10-N2-O2
MOLECULAR WEIGHT :
166.20
WISWESSER LINE NOTATION :
ZMVR BO1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
6000 mg/kg/22W-I
TOXIC EFFECTS :
Tumorigenic - neoplastic by RTECS criteria Lungs, Thorax, or Respiration - tumors
REFERENCE :
34ZRA9 "Proceedings of the Quadrennial Conference on Cancer, 3rd, 1965," Severi, L., ed., Perugia, Italy, Univ. of Perugia, 1966 Volume(issue)/page/year: -,869,1965

Safety Information

[ Hazard Codes ]:
Xi

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S36

[ RTECS ]:
BZ4700000

[ HS Code ]:
2928000090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 2-Methoxybenzoic acid
  • Methyl 2-methoxybenzoate
  • Ethyl 2-methoxybenzoate
  • o-Anisaldehyde

DownStream

  • 2-(2-methoxyphenyl)-5-phenyl-1,3,4-oxadiazole
  • 5-(2-METHOXYPHENYL)-4-(4-METHYLPHENYL)-4H-1,2,4-TRIAZOLE-3-THIOL
  • (6E)-6-(5-phenyl-3H-1,3,4-oxadiazol-2-ylidene)cyclohexa-2,4-dien-1-one
  • 2-(2-methoxyphenyl)-1,3,4-oxadiazole
  • 5-(2-Methoxyphenyl)-4-(4-methoxyphenyl)-4H-1,2,4-triazole-3-thiol
  • 5-(2-Methoxyphenyl)-1,3,4-oxadiazol-2-amine

Customs

[ HS Code ]: 2928000090

[ Summary ]:
2928000090 other organic derivatives of hydrazine or of hydroxylamine VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:20.0%

Related Compounds

  • 5-(Hydroxymethyl)-2-Methoxybenzoic Acid
  • 5-(methylthio)-o-anisic acid
  • 5-mercapto-o-anisic acid
  • 5-(ethylthio)-o-anisic acid
  • 3,4-Difluoro-o-anisic acid
  • 3,6-dichloro-o-anisic acid, compound with 2,2'-iminodiethanol (1:1)
  • 3-Amino-1-(4-bromo-2-fluorophenyl)propan-1-one
  • 3-Amino-1-(2-bromo-4-fluorophenyl)propan-1-one
  • 3-Amino-1-(2-bromo-5-fluorophenyl)propan-1-one
  • 3-Amino-1-(3-bromo-5-fluorophenyl)propan-1-one
  • 3-Amino-1-(4-bromo-3-fluorophenyl)propan-1-one
  • 3-Amino-1-(2-bromo-6-fluorophenyl)propan-1-one
  • 3-Amino-1-(2-bromo-3-fluorophenyl)propan-1-one
  • 2-(1-Aminoethyl)-4-bromo-6-methoxyphenol
  • O-[2-(2-bromo-5-methoxyphenyl)ethyl]hydroxylamine
  • O-[2-(2-bromo-6-methoxyphenyl)ethyl]hydroxylamine
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