Tetramethylammonium hydroxide
Suppliers
Names
[ CAS No. ]:
75-59-2
[ Name ]:
Tetramethylammonium hydroxide
[Synonym ]:
AR-300-49
tetreamethyl ammonium hydroxide
nmw-w
MFCD00008280
TMAH
TRITONNE
Developer
ocg945
TMNOH
AZ-300MIF
AZ-726
nmd3
EINECS 200-882-9
Chemical & Physical Properties
[ Density]:
0.866 g/mL at 25 °C
[ Boiling Point ]:
110 °C
[ Melting Point ]:
°C
[ Molecular Formula ]:
C4H13NO
[ Molecular Weight ]:
91.152
[ Flash Point ]:
80 °F
[ Exact Mass ]:
91.099716
[ PSA ]:
23.06000
[ LogP ]:
0.14560
[ Vapour Pressure ]:
17.5 mm Hg ( 20 °C)
[ Index of Refraction ]:
n20/D 1.384
[ Storage condition ]:
2-8°C
[ Stability ]:
Stable. Flammable. Incompatible with strong oxidizing agents, strong acids.
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- PA0875000
- CHEMICAL NAME :
- Methanaminium, N,N,N-trimethyl-, hydroxide
- CAS REGISTRY NUMBER :
- 75-59-2
- LAST UPDATED :
- 199710
- DATA ITEMS CITED :
- 9
- MOLECULAR FORMULA :
- C4-H12-N.H-O
- MOLECULAR WEIGHT :
- 91.18
- WISWESSER LINE NOTATION :
- 1K1&1&1 &Q
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 19 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 28,367,1926
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 1 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- 85IXA4 "Structure et Activite Pharmacodyanmique des Medicaments du Systeme Nerveux Vegetatif," Bovet, D., and F. Bovet-Nitti, New York, S. Karger, 1948 Volume(issue)/page/year: -,688,1948
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - guinea pig
- DOSE/DURATION :
- 25 mg/kg
- TOXIC EFFECTS :
- Skin and Appendages - dermatitis, other (after systemic exposure)
- REFERENCE :
- NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0570994
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Parenteral
- SPECIES OBSERVED :
- Amphibian - frog
- DOSE/DURATION :
- 5 mg/kg
- TOXIC EFFECTS :
- Vascular - BP elevation not characterized in autonomic section
- REFERENCE :
- 85IXA4 "Structure et Activite Pharmacodyanmique des Medicaments du Systeme Nerveux Vegetatif," Bovet, D., and F. Bovet-Nitti, New York, S. Karger, 1948 Volume(issue)/page/year: -,688,1948
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Unreported
- SPECIES OBSERVED :
- Amphibian - frog
- DOSE/DURATION :
- 1515 ug/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- 85IXA4 "Structure et Activite Pharmacodyanmique des Medicaments du Systeme Nerveux Vegetatif," Bovet, D., and F. Bovet-Nitti, New York, S. Karger, 1948 Volume(issue)/page/year: -,681,1948 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - A1009 No. of Facilities: 48 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 48 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - A1009 No. of Facilities: 105 (estimated) No. of Industries: 6 No. of Occupations: 16 No. of Employees: 6413 (estimated) No. of Female Employees: 1446 (estimated)
Safety Information
[ Symbol ]:
GHS02, GHS05, GHS06, GHS08, GHS09
[ Signal Word ]:
Danger
[ Hazard Statements ]:
H226-H300 + H310-H314-H331-H370-H372-H411
[ Precautionary Statements ]:
P260-P264-P273-P280-P301 + P310-P302 + P350
[ Target Organs ]:
Liver, thymus gland
[ Personal Protective Equipment ]:
Faceshields;full-face respirator (US);Gloves;Goggles;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
[ Hazard Codes ]:
T:Toxic; C:Corrosive;
[ Risk Phrases ]:
R20/21/22;R34
[ Safety Phrases ]:
S45-S36/37/39-S26-S16-S36/37
[ RIDADR ]:
UN 3286 3/PG 2
[ WGK Germany ]:
1
[ RTECS ]:
PA0875000
[ Packaging Group ]:
II
[ Hazard Class ]:
3
[ HS Code ]:
2923900090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2923900090
[ Summary ]:
2923900090 other quaternary ammonium salts and hydroxides。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%
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