4-(p-Methoxybenzoyl)morpholine

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Names

[ CAS No. ]:
7504-58-7

[ Name ]:
4-(p-Methoxybenzoyl)morpholine

[Synonym ]:
Anissaeuremorpholid
p-Anisic acid,morpholide

Chemical & Physical Properties

[ Density]:
1.167g/cm3

[ Boiling Point ]:
392.7ºC at 760 mmHg

[ Molecular Formula ]:
C12H15NO3

[ Molecular Weight ]:
221.25200

[ Flash Point ]:
191.3ºC

[ Exact Mass ]:
221.10500

[ PSA ]:
38.77000

[ LogP ]:
1.10550

[ Index of Refraction ]:
1.545

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
QE5550000
CHEMICAL NAME :
Morpholine, 4-(p-methoxybenzoyl)-
CAS REGISTRY NUMBER :
7504-58-7
LAST UPDATED :
199612
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C12-H15-N-O3
MOLECULAR WEIGHT :
221.28
WISWESSER LINE NOTATION :
T6N DOTJ AVR DO1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
720 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
BCPCA6 Biochemical Pharmacology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.1- 1958- Volume(issue)/page/year: 11,651,1962

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • morpholine
  • p-Anisic acid
  • 4-Methoxybenzyl alcohol
  • 4-Bromoanisole
  • carbon monoxide
  • 4-Iodoanisole
  • 4-methoxybenzoic acid 2,5-dioxo-1-pyrrolidinyl ester
  • 4-Methoxybenzaldehyde
  • (4-methoxyphenyl)-morpholin-4-yl-methanethione

DownStream

  • morpholine
  • 4-[(4-methoxyphenyl)methyl]morpholine
  • 4-Methoxybenzyl alcohol

Related Compounds

  • 4-p-methoxybenzoyl-5-methoxycarbonyl-3,5-dihydroxy-1-phenyl-2,5-dihydro-2-pyrrolone
  • 4-(p-methoxybenzoyl)-5-chloro-3-methyl-1-phenylpyrazole
  • (4-hydroxypiperidin-4-yl)-(4-methoxyphenyl)methanone,hydrochloride
  • 4-(P-TOLYL)MORPHOLINE
  • 4-[p-(Phenoxymethyl)benzyl]morpholine
  • 4-[p-(Phenoxymethyl)phenethyl]morpholine
  • 3-(Chloromethyl)-8-methoxyisoquinoline
  • Pyridine, 3-hydrazinyl-2-methoxy-6-methyl-
  • 1-Ethoxy-4-ethynyl-2-fluorobenzene
  • 1,3,6,8-Tetrafluorodibenzo-p-dioxin
  • 2-Ethoxy-1,3,4-trifluoro-5-nitrobenzene
  • 2-(2,3-Dimethoxyphenyl)-5,7-dimethyl-1H-benzo[d]imidazole
  • Ethyl 2-hydroxy-6-(trifluoromethyl)benzoate
  • 3-(Benzylamino)-5,5-dimethylhexanoic acid
  • 2-(Bromomethyl)-1,3-dichloro-4-fluorobenzene
  • Tert-butyl 2-aminooctanoate
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