2-HYDROXYETHYL (2-HYDROXYETHYL)-CARBAMATE

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Names

[ CAS No. ]:
7506-80-1

[ Name ]:
2-HYDROXYETHYL (2-HYDROXYETHYL)-CARBAMATE

[Synonym ]:
Thanol C 150
2-<N-(2-Hydroxy-ethyl)-carbamoyloxy>-ethanol
2-(hydroxyethoxycarboxamido)ethanol
(2-Hydroxy-aethyl)-carbamidsaeure-(2-hydroxy-aethylester)
(2-hydroxy-ethyl)-carbamic acid-(2-hydroxy-ethyl ester)
EINECS 231-361-4
2-Hydroxyethyl 2-hydroxyethylcarbamate

Chemical & Physical Properties

[ Density]:
1.259g/cm3

[ Boiling Point ]:
344.8ºC at 760 mmHg

[ Molecular Formula ]:
C5H11NO4

[ Molecular Weight ]:
149.14500

[ Flash Point ]:
162.3ºC

[ Exact Mass ]:
149.06900

[ PSA ]:
78.79000

[ Index of Refraction ]:
1.48

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
FB2050000
CHEMICAL NAME :
Carbamic acid, (2-hydroxyethyl)-, 2-hydroxyethyl ester
CAS REGISTRY NUMBER :
7506-80-1
BEILSTEIN REFERENCE NO. :
1812047
LAST UPDATED :
199701
DATA ITEMS CITED :
5
MOLECULAR FORMULA :
C5-H11-N-O4
MOLECULAR WEIGHT :
149.17

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
Standard Draize test
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rabbit
REFERENCE :
ATDAEI Acute Toxicity Data. Journal of the American College of Toxicology, Part B. (Mary Ann Liebert, Inc., 1651 Third Ave., New York, NY 10128) V.1- 1990- Volume(issue)/page/year: 1,195,1992
TYPE OF TEST :
Standard Draize test
ROUTE OF EXPOSURE :
Administration into the eye
SPECIES OBSERVED :
Rodent - rabbit
REFERENCE :
ATDAEI Acute Toxicity Data. Journal of the American College of Toxicology, Part B. (Mary Ann Liebert, Inc., 1651 Third Ave., New York, NY 10128) V.1- 1990- Volume(issue)/page/year: 1,195,1992 ** ACUTE TOXICITY DATA **
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
3700 uL/kg
TOXIC EFFECTS :
Sense Organs and Special Senses (Eye) - ptosis Behavioral - ataxia Gastrointestinal - other changes
REFERENCE :
ATDAEI Acute Toxicity Data. Journal of the American College of Toxicology, Part B. (Mary Ann Liebert, Inc., 1651 Third Ave., New York, NY 10128) V.1- 1990- Volume(issue)/page/year: 1,195,1992
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
8 mL/kg
TOXIC EFFECTS :
Lungs, Thorax, or Respiration - other changes Musculoskeletal - other changes
REFERENCE :
ATDAEI Acute Toxicity Data. Journal of the American College of Toxicology, Part B. (Mary Ann Liebert, Inc., 1651 Third Ave., New York, NY 10128) V.1- 1990- Volume(issue)/page/year: 1,195,1992

Synthetic Route

Precursor & DownStream

Precursor

  • Ethylene carbonate
  • 2-Aminoethanol

DownStream

  • oxazolidinone
  • 3-(2-CHLOROETHYL)OXAZOLIDIN-2-ONE

Related Compounds

  • Carbamic acid, (2-hydroxyethyl)-, octylester (9CI)
  • Carbamic acid,(2-hydroxyethyl)-, hexyl ester (9CI)
  • Carbamic acid,(2-hydroxyethyl)-, decyl ester (9CI)
  • propan-2-yl N-(2-hydroxyethyl)carbamate
  • tert-butyl cyclohexyl(2-hydroxyethyl)carbamate
  • methyl N-ethyl-N-(2-hydroxyethyl)carbamate
  • 2-cyclobutyl-7-ethyl-6-methyl-4H,5H,6H,7H-[1,2,4]triazolo[1,5-a]pyrimidine
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
  • tert-Butyl-DL-alanine
  • 6-Methyl-1H-imidazo[1,2-b]pyrazol-2(3H)-one