6-[(7R)-7-hydroxy-5,6-dihydropyrrolo[1,2-c]imidazol-7-yl]-N-methylnaphthalene-2-carboxamide

Names

[ CAS No. ]:
752243-39-3

[ Name ]:
6-[(7R)-7-hydroxy-5,6-dihydropyrrolo[1,2-c]imidazol-7-yl]-N-methylnaphthalene-2-carboxamide

[Synonym ]:
6-(7-Hydroxy-6,7-dihydro-5H-pyrrolo[1,2-c]imidazol-7-yl)-N-methyl-2-naphthamide
UNII-267WB8R4TI
2-Naphthalenecarboxamide, 6-(6,7-dihydro-7-hydroxy-5H-pyrrolo[1,2-c]imidazol-7-yl)-N-methyl-
TAK700
CS-0611
Orteronel,(R)
TAK-700 R-form
(R)-(-)-6-(7-hydroxy-6,7-dihydro-5H-pyrrolo[1,2-c]imidazol-7-yl)-N-methyl-2-naphthamide

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
685.1±45.0 °C at 760 mmHg

[ Molecular Formula ]:
C18H17N3O2

[ Molecular Weight ]:
307.346

[ Flash Point ]:
368.2±28.7 °C

[ Exact Mass ]:
307.132080

[ PSA ]:
67.15000

[ LogP ]:
-0.13

[ Vapour Pressure ]:
0.0±2.2 mmHg at 25°C

[ Index of Refraction ]:
1.695

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • TAK-700 (Orteronel)
  • 6-Bromo-2-naphthoic acid
  • 6-bromo-N,N-diisopropyl-2-naphthamide
  • 6-Bromo-N-methyl-2-naphthamide
  • N,N-diisopropyl-6-[1-hydroxy-1-(1-trityl-1H-imidazol-4-yl)methyl]-2-naphthamide
  • N,N-diisopropyl-6-[(1-trityl-1H-imidazol-4-yl)carbonyl]-2-naphthamide
  • 1-(1H-imidazol-4-yl)prop-2-en-1-one
  • 6-bromonaphthalene-2-carbonyl chloride

DownStream

Related Compounds

  • (3-(N-(m-Tolyl)sulfamoyl)phenyl)boronic acid
  • tert-butyl ((1-(5-nitro-1H-benzo[d]imidazol-2-yl)piperidin-3-yl)methyl)carbamate
  • Tert-butyl ((1-(5-nitrobenzo[d]oxazol-2-yl)piperidin-3-yl)methyl)carbamate
  • Tert-butyl ((1-((2-chloropyrimidin-4-yl)methyl)piperidin-3-yl)methyl)carbamate
  • Tert-butyl ((1-(5-nitropyridin-2-yl)pyrrolidin-2-yl)methyl)carbamate
  • Tert-butyl ((1-(3-chloroquinoxalin-2-yl)pyrrolidin-2-yl)methyl)carbamate
  • Tert-butyl ((1-(2,3-dihydrobenzo[b][1,4]dioxine-6-carbonyl)pyrrolidin-3-yl)methyl)carbamate
  • Tert-butyl ((1-(1,1-dioxidobenzo[d]isothiazol-3-yl)pyrrolidin-3-yl)methyl)carbamate
  • Tert-butyl ((1-(2-(furan-2-yl)-2-oxoethyl)pyrrolidin-3-yl)methyl)carbamate
  • Tert-butyl ((1-(6-bromopyridin-2-yl)piperidin-4-yl)methyl)carbamate
The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.