Methyl L-phenylalaninate hydrochloride

Suppliers

Names

[ CAS No. ]:
7524-50-7

[ Name ]:
Methyl L-phenylalaninate hydrochloride

[Synonym ]:
L-Phenylalanine, methyl ester, hydrochloride (1:1)
Methyl L-phenylalaninate hydrochloride
EINECS 231-383-4
Phenylalanine, methyl ester, hydrochloride (1:1)
L-Phenylalanine methyl ester hydrochloride
MFCD00012489
methyl (2S)-2-amino-3-phenylpropanoate,hydrochloride
H-Phe-OMe.HCl
H-Phe-OmeHCl

Chemical & Physical Properties

[ Boiling Point ]:
264.2ºC at 760 mmHg

[ Melting Point ]:
156-160ºC

[ Molecular Formula ]:
C10H14ClNO2

[ Molecular Weight ]:
215.677

[ Flash Point ]:
126ºC

[ Exact Mass ]:
215.071304

[ PSA ]:
52.32000

[ LogP ]:
2.23170

[ Index of Refraction ]:
38 ° (C=2, EtOH)

MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xi: Irritant;C: Corrosive;

[ Risk Phrases ]:
36/37/38-34

[ Safety Phrases ]:
S24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
29224995

Synthetic Route

Precursor & DownStream

Precursor

  • L-Phenylalanine
  • Methanol
  • methyl N-benzyl-L-phenylalaninate
  • L-Phenylalanine hydrochloride
  • Boc-L-phenylalanine methyl ester
  • isobutanol
  • Methyl N-acetyl-L-phenylalaninate
  • (S)-methyl 3-phenyl-2-(2-(trimethylsilyl)ethylsulfonamido)propanoate

DownStream

  • H-Phe-Leu-OH
  • Boc-N-Me-Phe-OH
  • H-Phe-ol
  • (2S,5S)-(-)-2-tert-Butyl-3-methyl-5-benzyl-4-imidazolidinone
  • (S)-2-((TERT-BUTOXYCARBONYL)AMINO)-3-PHENYLPROPYL 4-METHYLBENZENESULFONATE
  • H-Phe-ObzlTos
  • methyl 2-[[(E)-3-[bis(2-chloroethyl)amino]prop-2-enoyl]amino]-3-phenyl-propanoate
  • 1-[(2S)-1-hydroxy-3-phenylpropan-2-yl]-3-phenylurea
  • L-Phenylalanine,N-acetyl-, hydrazide
  • Methyl cinnamate

Customs

[ HS Code ]: 2922499990

[ Summary ]:
HS:2922499990 other amino-acids, other than those containing more than one kind of oxygen function, and their esters; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:6.5% General tariff:30.0%

Articles

Transport and signaling via the amino acid binding site of the yeast Gap1 amino acid transceptor.

Nat. Chem. Biol. 5 , 45-52, (2009)

Transporter-related nutrient sensors, called transceptors, mediate nutrient activation of signaling pathways through the plasma membrane. The mechanism of action of transporting and nontransporting tr...

N-methyl phenylalanine-rich peptides as highly versatile blood-brain barrier shuttles.

J. Med. Chem. 53 , 2354-63, (2010)

Here we studied the capacity of N-MePhe-(N-MePhe)(3)-CONH(2), Cha-(N-MePhe)(3)-CONH(2), and 2Nal-(N-MePhe)(3)-CONH(2) to carry various drugs (cargos) in in vitro blood-brain barrier (BBB) models in or...

Spectrum of toxicities of amino acid methyl esters for myeloid cells is determined by distinct metabolic pathways.

Blood 79(4) , 964-71, (1992)

L-leucine methyl ester (Leu-OMe), Leu-Leu-OMe, Phe-OMe, and Glu-(OMe)2 are toxic to mononuclear phagocytes (M phi) and neutrophils. In the present studies, the mechanism of this toxicity was examined....


More Articles


Related Compounds

  • Methyl L-phenylalaninate hydrochloride (1:1)
  • Methyl L-phenylalaninate hydrochloride (1:1)
  • Methyl α-methyl-L-phenylalaninate hydrochloride (1:1)
  • n-me-phe-ome hcl
  • Methyl L-phenylalaninate
  • Methyl 3-bromo-L-phenylalaninate hydrochloride