p-Nitrobenzyl (5R,6S)-2-(diphenylphosphoryloxy)-6-((1R)-1-hydroxyethyl)carbapen-2-em-3-carboxylate

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Names

[ CAS No. ]:
75321-08-3

[ Name ]:
p-Nitrobenzyl (5R,6S)-2-(diphenylphosphoryloxy)-6-((1R)-1-hydroxyethyl)carbapen-2-em-3-carboxylate

[Synonym ]:
ac-4678

Chemical & Physical Properties

[ Density]:
1.49

[ Boiling Point ]:
721.2ºC at 760 mmHg

[ Molecular Formula ]:
C28H25N2O10P

[ Molecular Weight ]:
580.47900

[ Flash Point ]:
390ºC

[ Exact Mass ]:
580.12500

[ PSA ]:
167.23000

[ LogP ]:
5.20490

[ Index of Refraction ]:
1.661

Synthetic Route

Precursor & DownStream

Precursor

  • P-NITROBENZYL (2R,5R,6S)-6-[(R)-1-HYDROXYETHYL]-3,7-DIOXO-1-AZABICYCLO[3.2.0]HEPTANE-2-CARBOXYLATE
  • Diphenyl chlorophosphate
  • (3S,4R)-3-[(R)-1-hydroxyethyl)-4-[3-(4-nitrobenzyl)oxycarbonyl-2-oxo-3-diazopropyl]azetidin-2-one
  • (S)-1-(tert-butyldimethylsilyl)-4-((2-(trimethylsilyl)-1,3-dithian-2-yl)methyl)azetidin-2-one
  • (3S,4R)-1-(t-butyldimethylsilyl)-3-[(R)-1-hydroxyethyl]-4-(2-oxo-2-trimethylsilylethyl)-azetidin-2-one
  • (3S,4R)-4-(2-(1H-imidazol-1-yl)-2-oxoethyl)-1-(tert-butyldimethylsilyl)-3-((R)-1-hydroxyethyl)azetidin-2-one
  • (3S,4R)-3-acetyl-1-(tert-butyldimethylsilyl)-4-((2-(trimethylsilyl)-1,3-dithian-2-yl)methyl)azetidin-2-one

DownStream

  • Imipenem

Related Compounds

  • Methyl 2-[(pent-4-yn-1-yl)amino]pyridine-4-carboxylate
  • 2-[(Pent-4-yn-1-yl)amino]pyridine-3-carboxylic acid
  • 4-[(Pent-4-yn-1-yl)amino]pyridine-2-carboxylic acid
  • 6-[(Pent-4-yn-1-yl)amino]pyridine-2-carboxylic acid
  • 6-[(Pent-4-yn-1-yl)amino]pyrazine-2-carboxylic acid
  • 5-Chloro-2-[(pent-4-yn-1-yl)amino]benzoic acid
  • (2R,3S)-2-Phenyl-3-(trifluoromethyl)piperazine
  • 4-Methyl-2-[(pent-4-yn-1-yl)amino]pyrimidine-5-carboxylic acid
  • 5-[(Pent-4-yn-1-yl)amino]pyrazine-2-carboxylic acid
  • 6-[(Pent-4-yn-1-yl)amino]pyridazine-3-carboxylic acid
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