p-Nitrobenzyl (5R,6S)-2-(diphenylphosphoryloxy)-6-((1R)-1-hydroxyethyl)carbapen-2-em-3-carboxylate

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Names

[ CAS No. ]:
75321-08-3

[ Name ]:
p-Nitrobenzyl (5R,6S)-2-(diphenylphosphoryloxy)-6-((1R)-1-hydroxyethyl)carbapen-2-em-3-carboxylate

[Synonym ]:
ac-4678

Chemical & Physical Properties

[ Density]:
1.49

[ Boiling Point ]:
721.2ºC at 760 mmHg

[ Molecular Formula ]:
C28H25N2O10P

[ Molecular Weight ]:
580.47900

[ Flash Point ]:
390ºC

[ Exact Mass ]:
580.12500

[ PSA ]:
167.23000

[ LogP ]:
5.20490

[ Index of Refraction ]:
1.661

Synthetic Route

Precursor & DownStream

Precursor

  • P-NITROBENZYL (2R,5R,6S)-6-[(R)-1-HYDROXYETHYL]-3,7-DIOXO-1-AZABICYCLO[3.2.0]HEPTANE-2-CARBOXYLATE
  • Diphenyl chlorophosphate
  • (3S,4R)-3-[(R)-1-hydroxyethyl)-4-[3-(4-nitrobenzyl)oxycarbonyl-2-oxo-3-diazopropyl]azetidin-2-one
  • (S)-1-(tert-butyldimethylsilyl)-4-((2-(trimethylsilyl)-1,3-dithian-2-yl)methyl)azetidin-2-one
  • (3S,4R)-1-(t-butyldimethylsilyl)-3-[(R)-1-hydroxyethyl]-4-(2-oxo-2-trimethylsilylethyl)-azetidin-2-one
  • (3S,4R)-4-(2-(1H-imidazol-1-yl)-2-oxoethyl)-1-(tert-butyldimethylsilyl)-3-((R)-1-hydroxyethyl)azetidin-2-one
  • (3S,4R)-3-acetyl-1-(tert-butyldimethylsilyl)-4-((2-(trimethylsilyl)-1,3-dithian-2-yl)methyl)azetidin-2-one

DownStream

  • Imipenem

Related Compounds

  • 2-Bromo-6-chlorobenzenesulfonamide
  • 2-Methyl-4-(trifluoromethyl)benzene-1-sulfonyl chloride
  • 5-(4-Methylpiperazin-1-yl)-2-(piperidin-3-yl)pyridazin-3(2H)-one
  • 2-Phenyl-3-azabicyclo[3.2.1]octane
  • 9-(Trifluoromethyl)-6-azaspiro[3.5]nonane
  • 3-Bromo-2,2-difluoropropan-1-ol
  • 1-[2-(1H-Imidazol-5-yl)ethyl]-3-(2-methoxyethyl)thiourea
  • 2-[(5-bromo-1H-indol-3-yl)methyl]-2-acetamidopropanedioic acid
  • 2-Amino-5,5-dimethylhexane-1,4-diol
  • Ethyl 2-(cyclopropanesulfonyl)-2-methylpropanoate
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