EHT 1864

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Names

[ CAS No. ]:
754240-09-0

[ Name ]:
EHT 1864

[Synonym ]:
4H-Pyran-4-one, 2-(4-morpholinylmethyl)-5-[[5-[[7-(trifluoromethyl)-4-quinolinyl]thio]pentyl]oxy]-, hydrochloride (1:2)
2-(4-Morpholinylmethyl)-5-[(5-{[7-(trifluoromethyl)-4-quinolinyl]sulfanyl}pentyl)oxy]-4H-pyran-4-one dihydrochloride
2-(Morpholin-4-ylmethyl)-5-[(5-{[7-(trifluoromethyl)quinolin-4-yl]sulfanyl}pentyl)oxy]-4H-pyran-4-one dihydrochloride
eht 1864
EHT-1864

Chemical & Physical Properties

[ Molecular Formula ]:
C25H29Cl2F3N2O4S

[ Molecular Weight ]:
581.475

[ Exact Mass ]:
580.117737

[ PSA ]:
90.10000

[ LogP ]:
6.92230

[ Appearance of Characters ]:
white to beige

[ Storage condition ]:
2-8°C

[ Water Solubility ]:
H2O: soluble10mg/mL, clear

MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
NONH for all modes of transport

Articles

Gq-mediated Akt translocation to the membrane: a novel PIP3-independent mechanism in platelets.

Blood 125(1) , 175-84, (2015)

Akt is an important signaling molecule regulating platelet aggregation. Akt is phosphorylated after translocation to the membrane through Gi signaling pathways by a phosphatidylinositol-3,4,5-trisphos...

Instructive roles for cytokine-receptor binding parameters in determining signaling and functional potency.

Sci. Signal. 8 , ra114, (2015)

Cytokines dimerize cell surface receptors to activate signaling and regulate many facets of the immune response. Many cytokines have pleiotropic effects, inducing a spectrum of redundant and distinct ...

An integrated imaging approach to the study of oxidative stress generation by mitochondrial dysfunction in living cells.

Environ. Health Perspect. 118 , 902-8, (2010)

The mechanisms of action of many environmental agents commonly involve oxidative stress resulting from mitochondrial dysfunction. Zinc is a common environmental metallic contaminant that has been impl...


More Articles


Related Compounds

  • EHT 5372
  • EHT-6706 dihydrochloride
  • EHT 5372
  • CGP 71683 HCl
  • Titanium ethylhexoxide
  • 7-ethoxy-4-(3,4,5-trimethoxybenzyl)isoquinolin-8-amine
  • trans-Ethyl 2-(2-methoxyphenyl)cyclopropanecarboxylate
  • 2-Bromo-3-(bromomethyl)-5-(difluoromethyl)-6-methylpyridine
  • 5-(Difluoromethyl)-3-iodo-4-(trifluoromethyl)pyridin-2-amine
  • 2-Amino-3-(chloromethyl)-6-(difluoromethyl)isonicotinonitrile
  • 2-(6-Cyano-5-(difluoromethyl)-4-nitropyridin-3-yl)acetic acid
  • 2-Bromo-4-(difluoromethoxy)-3-fluorophenol
  • 2-Amino-4-(difluoromethyl)-6-iodonicotinaldehyde
  • 6-Amino-2-(difluoromethyl)-5-iodonicotinic acid
  • 5-(Difluoromethyl)-6-(trifluoromethyl)pyridine-2,3-diamine
  • 3-(Difluoromethyl)-4-(hydroxymethyl)-6-methoxypicolinonitrile
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