EHT 1864

Suppliers

Names

[ Name ]:
EHT 1864

[Synonym ]:
4H-Pyran-4-one, 2-(4-morpholinylmethyl)-5-[[5-[[7-(trifluoromethyl)-4-quinolinyl]thio]pentyl]oxy]-, hydrochloride (1:2)
2-(4-Morpholinylmethyl)-5-[(5-{[7-(trifluoromethyl)-4-quinolinyl]sulfanyl}pentyl)oxy]-4H-pyran-4-one dihydrochloride
2-(Morpholin-4-ylmethyl)-5-[(5-{[7-(trifluoromethyl)quinolin-4-yl]sulfanyl}pentyl)oxy]-4H-pyran-4-one dihydrochloride
eht 1864
EHT-1864

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₅H₂₉Cl₂F₃N₂O₄S

[ Molecular Weight ]:
581.475

[ Exact Mass ]:
580.117737

[ PSA ]:
90.10000

[ LogP ]:
6.92230

[ Appearance of Characters ]:
white to beige

[ Storage condition ]:
2-8°C

[ Water Solubility ]:
H2O: soluble10mg/mL, clear

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
NONH for all modes of transport

Articles

Gq-mediated Akt translocation to the membrane: a novel PIP3-independent mechanism in platelets.

Blood 125(1) , 175-84, (2015)

Akt is an important signaling molecule regulating platelet aggregation. Akt is phosphorylated after translocation to the membrane through Gi signaling pathways by a phosphatidylinositol-3,4,5-trisphos...

Instructive roles for cytokine-receptor binding parameters in determining signaling and functional potency.

Sci. Signal. 8 , ra114, (2015)

Cytokines dimerize cell surface receptors to activate signaling and regulate many facets of the immune response. Many cytokines have pleiotropic effects, inducing a spectrum of redundant and distinct ...

An integrated imaging approach to the study of oxidative stress generation by mitochondrial dysfunction in living cells.

Environ. Health Perspect. 118 , 902-8, (2010)

The mechanisms of action of many environmental agents commonly involve oxidative stress resulting from mitochondrial dysfunction. Zinc is a common environmental metallic contaminant that has been impl...