Protein-arginine deiminase

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Names

[ CAS No. ]:
75536-80-0

[ Name ]:
Protein-arginine deiminase

Chemical & Physical Properties

[ Appearance of Characters ]:
buffered aqueous glycerol solution

[ Storage condition ]:
−70°C

Safety Information

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
1

Articles

Evidence of fibrinogen as a target of citrullination in IgM rheumatoid factor-positive polyarticular juvenile idiopathic arthritis.

Pediatr. Rheumatol. Online J. 9 , 8, (2011)

Several studies have noted the significance of measuring anti-cyclic citrullinated peptide (CCP) antibodies in juvenile idiopathic arthritis (JIA) as an important indicator for destructive disease, as...

The human peptidylarginine deiminases type 2 and type 4 have distinct substrate specificities

Biochim. Biophys. Acta 1844(4) , 829-36, (2014)

Human peptidylarginine deiminases (hPADs) have been implicated in several diseases, particularly in rheumatoid arthritis. Since hPAD2 and hPAD4 are the isotypes expressed in the inflamed joints of RA ...

Retinal deimination and PAD2 levels in retinas from donors with age-related macular degeneration (AMD)

Exp. Eye Res. 111 , 71-8, (2013)

Deimination is a form of protein posttranslational modification carried out by the peptidyl arginine deiminases (PADs) enzymes. PAD2 is the principal deiminase expressed in the retina. Elevated levels...

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