4-METHOXY-1-METHYL-1H-INDOLE

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Names

[ CAS No. ]:
7556-35-6

[ Name ]:
4-METHOXY-1-METHYL-1H-INDOLE

[Synonym ]:
4-methoxyl-N-methylindole
MFCD00010679
4-Methoxy-1-methyl-indol
1-Methyl-4-methoxy-indol
4-Methoxy-1-methyl-1H-indole
4-methoxy-1-methyl-indole
1-Methyl-4-methoxy-1H-indole

Chemical & Physical Properties

[ Density]:
1.06g/cm3

[ Boiling Point ]:
285.6ºC at 760 mmHg

[ Melting Point ]:
89-91ºC

[ Molecular Formula ]:
C10H11NO

[ Molecular Weight ]:
161.20000

[ Flash Point ]:
126.5ºC

[ Exact Mass ]:
161.08400

[ PSA ]:
14.16000

[ LogP ]:
2.18690

[ Index of Refraction ]:
1.551

MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xi

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S37-S39

[ RIDADR ]:
NONH for all modes of transport

Synthetic Route

Precursor & DownStream

Precursor

  • 4-Hydroxyindole
  • methyl iodide
  • 4-Methoxyindole
  • 2,4,6-trichlorophenyl 1-bromo-2-((3-methoxyphenyl)(methyl)amino)ethanesulfonate
  • 4-Methoxy-2-indolinone
  • 2-METHOXY-6-NITROPHENYLACETIC ACID
  • 2-(2-methoxy-6-nitrophenyl)acetonitrile
  • 2-chloromethyl-3-nitro-anisole
  • 4-Methoxy-1-methylindolin-2-one

DownStream

  • 1-Methyl-1H-indol-4-ol

Articles

Development and validation of an HPLC method for the simultaneous quantification of indole-3-carbinol acetate, indole-3-carbinol, and 3,3'-diindolylmethane in mouse plasma, liver, and kidney tissues.

J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci. 958 , 1-9, (2014)

A novel Indole-3-carbinol derivative (I3C) prodrug, indole-3-carbinol acetate (I3CA), was synthesized and a rapid high-performance liquid chromatography (HPLC) method for the quantification of I3CA, I...

Further observations on and novel products from acid-catalysed indole-pyrrole condensations: formation of pyrrolo [2, 3-b] carbazoles. Chunchatprasert L and Shannon PVR.

J. Chem. Soc. Perkin Trans. I 13 , 1765-72, (1994)


More Articles


Related Compounds

  • 4-Methoxy-1-methyl-1H-indole
  • 4-METHOXY-1-METHYL-1H-INDOLE-3-CARBALDEHYDE
  • 4-METHOXY-1-METHYL-1H-INDOLE-2-CARBOXYLIC ACID
  • Methyl 4-methoxy-1-methyl-1H-indole-2-carboxylate
  • 1H-Indole-3-carboxylic acid, 4-methoxy-1-methyl
  • 4-methoxy-1-methyl-2-phenylindole