ACRIDINE, 9-(3-PYRIDYLAMINO)-

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Names

[ CAS No. ]:
75775-64-3

[ Name ]:
ACRIDINE, 9-(3-PYRIDYLAMINO)-

[Synonym ]:
9-(PYRIDIN-3-YLAMINO)ACRIDINE
acridin-9-yl-pyridin-3-yl-amine
9-(3-Pyridylamino)acridine
ACRIDINE,9-(3-PYRIDYLAMINO)
9-(3-Pyridylamino)acridin

Chemical & Physical Properties

[ Density]:
1.291g/cm3

[ Boiling Point ]:
462.7ºC at 760mmHg

[ Molecular Formula ]:
C18H13N3

[ Molecular Weight ]:
271.31600

[ Flash Point ]:
233.7ºC

[ Exact Mass ]:
271.11100

[ PSA ]:
37.81000

[ LogP ]:
4.59960

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
AR9486650
CHEMICAL NAME :
Acridine, 9-(3-pyridylamino)-
CAS REGISTRY NUMBER :
75775-64-3
BEILSTEIN REFERENCE NO. :
0409914
LAST UPDATED :
199612
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C18-H13-N3
MOLECULAR WEIGHT :
271.34
WISWESSER LINE NOTATION :
T C666 BNJ IM- CT6NJ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD10 - Lethal Dose
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
>500 mg/kg
TOXIC EFFECTS :
Tumorigenic - active as anti-cancer agent

MUTATION DATA

TYPE OF TEST :
DNA damage
TEST SYSTEM :
Mammal - species unspecified Lymphocyte
DOSE/DURATION :
13 umol/L
REFERENCE :
JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 24,170,1981

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 9-Chloroacridine

DownStream

Related Compounds

  • 9-Acridinamine, N-3-pyridinyl-, monohydrochloride (9CI)
  • Acridine, 9-(3,4-dihydro-6-methoxy-1(2H)-quinolinyl)-
  • Nitracrine
  • acridin-9-yl-[3-(2-chloroethylsulfanyl)propyl]azanium,chloride
  • diethyl-[3-[(1-nitroacridin-9-yl)azaniumyl]propyl]azanium,dichloride
  • N',N'-dimethyl-N-(4-nitroacridin-9-yl)propane-1,3-diamine
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
  • tert-Butyl-DL-alanine
  • 2-(2-Bromo-3-methylcyclopent-2-en-1-yl)acetaldehyde
  • 1-(2-Trifluoromethylbenzyl)cyclopropylamine