1-Benzyl 2-methyl (2S)-5-oxo-1,2-pyrrolidinedicarboxylate

Names

[ CAS No. ]:
75857-94-2

[ Name ]:
1-Benzyl 2-methyl (2S)-5-oxo-1,2-pyrrolidinedicarboxylate

[Synonym ]:
N-benzyloxycarbonyl-phenylalaninol
N-Benzyloxycarbonyl-propargylglycin
methyl N-benzyloxycarbonyl-L-pyroglutamate
methyl L-1-benzyloxycarbonylpyroglutamate
N-carbamoyl-L-pyroglutamate
N-benzyloxycarbonylpyroglutamate methyl ester

Chemical & Physical Properties

[ Molecular Formula ]:
C14H15NO5

[ Molecular Weight ]:
277.27300

[ Exact Mass ]:
277.09500

[ PSA ]:
72.91000

[ LogP ]:
1.42510

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • Z-Pyr-OH
  • methyl iodide
  • Benzyl chloroformate
  • Methyl L-Pyroglutamate
  • Dibenzyl dicarbonate
  • Cbz-Gln-OMe
  • (S)-1-Benzyl 2-methyl pyrrolidine-1,2-dicarboxylate
  • L-Pyroglutamicacid
  • Proline
  • Z-Glu-OMe

DownStream

  • Methyl L-Pyroglutamate
  • L-Glutamic acid:Hcl (17O4)

Related Compounds

  • 3-[2-(3-{[(6-Tert-butylpyridazin-3-yl)oxy]methyl}pyrrolidin-1-yl)-2-oxoethyl]-6-methyl-3,4-dihydropyrimidin-4-one
  • 3-[(1-Benzoylpyrrolidin-3-yl)methoxy]-6-cyclopropylpyridazine
  • 3-Cyclopropyl-6-{[1-(2-fluorobenzoyl)pyrrolidin-3-yl]methoxy}pyridazine
  • 3-Cyclopropyl-6-{[1-(3-fluorobenzoyl)pyrrolidin-3-yl]methoxy}pyridazine
  • 3-Cyclopropyl-6-{[1-(4-fluorobenzoyl)pyrrolidin-3-yl]methoxy}pyridazine
  • 3,5-difluoro-N-[(oxan-4-yl)methyl]benzene-1-sulfonamide
  • 3-Tert-butyl-6-{[1-(2-methanesulfonylbenzoyl)pyrrolidin-3-yl]methoxy}pyridazine
  • 4-[({2-Tert-butylimidazo[1,2-b]pyridazin-6-yl}oxy)methyl]-1-(cyclopropanesulfonyl)piperidine
  • 4-({imidazo[1,2-b]pyridazin-6-yloxy}methyl)-1-(1-methyl-1H-imidazole-4-carbonyl)piperidine
  • 3-cyclopropyl-6-({1-[(1,3,5-trimethyl-1H-pyrazol-4-yl)sulfonyl]pyrrolidin-3-yl}methoxy)pyridazine
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