Norastemizole Hydrobromide

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Names

[ CAS No. ]:
75970-64-8

[ Name ]:
Norastemizole Hydrobromide

[Synonym ]:
(1-(4-fluorobenzyl)-1H-benzimidazol-2-yl)-(4-piperidinyl)amine dihydrobromide
1-(4-fluorobenzyl)-N-piperidin-4-yl-1H-benzimidazol-2-amine dihydrobromide
1-<(4-fluorophenyl)methyl>-4-(4-piperidinyl)-1H-benzimidazol-2-amine dyhydrobromide
1-[(4-Fluorophenyl)Methyl]-N-4-piperidinyl-1H-benziMidazol-2-aMine HydrobroMide
1-(4-fluorophenylmethyl)-N-(4-piperidinyl)-1H-benzimidazol-2-amine dihydrobromide
norastemizole
1-<(4-fluorophenyl)methyl>-4-(4-piperidinyl)-1H-benzimidazol-2-amine dihydrobromide

Chemical & Physical Properties

[ Boiling Point ]:
519.8ºC at 760 mmHg

[ Melting Point ]:
170-178ºC

[ Molecular Formula ]:
C19H23Br2FN4

[ Molecular Weight ]:
486.21900

[ Flash Point ]:
268.2ºC

[ Exact Mass ]:
484.02700

[ PSA ]:
41.88000

[ LogP ]:
5.70560

Synthetic Route

Precursor & DownStream

Precursor

  • 4-[[1-[(4-FLUOROPHENYL)-METHYL]-1H-BENZIMIDAZOLE-2-YL]AMINO]-1-PIPERIDINECARBOXYLIC ACID ETHYL ESTER
  • ethyl 4-(1H-benzimidazol-2-ylamino)piperidine-1-carboxylate
  • 4-Fluorobenzyl chloride
  • N-Carbethoxy-4-amino-piperidone
  • ethyl 4-isothiocyanatopiperidine-1-carboxylate
  • ethyl 4-{[(2-aminophenyl)aminothioxomethyl]amino}-1-piperidinecarboxylate
  • 2-Hydroxybenzimidazole
  • 2-Chlorobenzimidazole
  • 3-[(4-fluorophenyl)methyl]-1H-benzimidazol-2-one
  • 1-(4-Fluorobenzyl)-2-chloro-benzimidazole

DownStream

  • Astemizole
  • O-Desmethyl Astemizole
  • 1-[(4-Fluorophenyl)methyl]-N-[1-[2-(2-pyridinyl)ethyl]-4-piperidinyl]-1H-benzimidazol-2-amine

Related Compounds

  • norastemizole
  • Xylopropamine Hydrobromide
  • Anisodamine hydrobromide
  • metazocine hydrobromide
  • hippeastrine hydrobromide
  • Rubigervine hydrobromide
  • 4-[1-Methyl-2-(4-methyl-4H-1,2,4-triazol-3-yl)ethyl]-2(1h)-pyridinone
  • 5-Bromo-7-chloro-2-methoxyquinoxaline
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • 1-(2-(Bromomethyl)-3-mercaptophenyl)-1-chloropropan-2-one
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • [3-(1,1-Difluoroethyl)-1,2,4-oxadiazol-5-yl]methanamine hydrochloride
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide