Norastemizole Hydrobromide

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Names

[ CAS No. ]:
75970-64-8

[ Name ]:
Norastemizole Hydrobromide

[Synonym ]:
(1-(4-fluorobenzyl)-1H-benzimidazol-2-yl)-(4-piperidinyl)amine dihydrobromide
1-(4-fluorobenzyl)-N-piperidin-4-yl-1H-benzimidazol-2-amine dihydrobromide
1-<(4-fluorophenyl)methyl>-4-(4-piperidinyl)-1H-benzimidazol-2-amine dyhydrobromide
1-[(4-Fluorophenyl)Methyl]-N-4-piperidinyl-1H-benziMidazol-2-aMine HydrobroMide
1-(4-fluorophenylmethyl)-N-(4-piperidinyl)-1H-benzimidazol-2-amine dihydrobromide
norastemizole
1-<(4-fluorophenyl)methyl>-4-(4-piperidinyl)-1H-benzimidazol-2-amine dihydrobromide

Chemical & Physical Properties

[ Boiling Point ]:
519.8ºC at 760 mmHg

[ Melting Point ]:
170-178ºC

[ Molecular Formula ]:
C19H23Br2FN4

[ Molecular Weight ]:
486.21900

[ Flash Point ]:
268.2ºC

[ Exact Mass ]:
484.02700

[ PSA ]:
41.88000

[ LogP ]:
5.70560

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 4-[[1-[(4-FLUOROPHENYL)-METHYL]-1H-BENZIMIDAZOLE-2-YL]AMINO]-1-PIPERIDINECARBOXYLIC ACID ETHYL ESTER
  • ethyl 4-(1H-benzimidazol-2-ylamino)piperidine-1-carboxylate
  • 4-Fluorobenzyl chloride
  • N-Carbethoxy-4-amino-piperidone
  • ethyl 4-isothiocyanatopiperidine-1-carboxylate
  • ethyl 4-{[(2-aminophenyl)aminothioxomethyl]amino}-1-piperidinecarboxylate
  • 2-Hydroxybenzimidazole
  • 2-Chlorobenzimidazole
  • 3-[(4-fluorophenyl)methyl]-1H-benzimidazol-2-one
  • 1-(4-Fluorobenzyl)-2-chloro-benzimidazole

DownStream

  • Astemizole
  • O-Desmethyl Astemizole
  • 1-[(4-Fluorophenyl)methyl]-N-[1-[2-(2-pyridinyl)ethyl]-4-piperidinyl]-1H-benzimidazol-2-amine

Related Compounds

  • norastemizole
  • Xylopropamine Hydrobromide
  • Anisodamine hydrobromide
  • metazocine hydrobromide
  • hippeastrine hydrobromide
  • Rubigervine hydrobromide
  • [1-(2-Fluoropyridin-4-yl)piperidin-4-yl]methanol
  • N-butyl-N-ethyl-2-fluoropyridin-4-amine
  • 2-[3-Fluoro-4-(trifluoromethyl)phenyl]-3-methylbutanoic acid
  • (3I(2),5I+/-,6I(2),25S)-6-Hydroxyspirostan-3-yl O-I(2)-D-glucopyranosyl-(1a2)-O-[I(2)-D-glucopyranosyl-(1a3)]-O-I(2)-D-glucopyranosyl-(1a4)-I(2)-D-galactopyranoside
  • 1,2,3,4,5,6,7,8,9-Nonachlorodecane
  • 5,5-Dimethyl-2-[3-(2-propyn-1-yloxy)-1-propyn-1-yl]-1,3,2-dioxaborinane
  • 2-Amino-5-[3-fluoro-4-(trifluoromethyl)phenyl]-1,3,4-thiadiazole
  • 2,5-Bis(2-chloroethyl) 2,5-pyridinedicarboxylate
  • N-tert-butyl-2-fluoropyridin-4-amine
  • 4-(2-Ethylpiperidin-1-yl)-2-fluoropyridine
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