Amolanone

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Names

[ CAS No. ]:
76-65-3

[ Name ]:
Amolanone

[Synonym ]:
3-(2-diethylaminoethyl)-3-phenyl-benzofuran-2-one
Amocaine
Amethone
3-(2-Diethylaminoethyl)-3-phenyl-2(3H)-benzofuranone
3-(2-Diaethylamino-aethyl)-3-phenyl-3H-benzofuran-2-on
AP-43
3-(2-diethylamino-ethyl)-3-phenyl-3H-benzofuran-2-one
3-[2-(Diethylamino)ethyl]-3-phenylbenzofuran-2(3H)-one
3-(2-diethylaminoethyl)-3-phenyl-1-benzofuran-2-one

Chemical & Physical Properties

[ Density]:
1.106 g/cm3

[ Boiling Point ]:
413.3ºC at 760 mmHg

[ Molecular Formula ]:
C20H23NO2

[ Molecular Weight ]:
309.40200

[ Flash Point ]:
133.4ºC

[ Exact Mass ]:
309.17300

[ PSA ]:
29.54000

[ LogP ]:
3.62360

[ Index of Refraction ]:
1.568

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
DF7875000
CHEMICAL NAME :
2(3H)-Benzofuranone, 3-(beta-diethylaminoethyl)-3-phenyl-
CAS REGISTRY NUMBER :
76-65-3
BEILSTEIN REFERENCE NO. :
0287893
LAST UPDATED :
199612
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C20-H23-N-O2
MOLECULAR WEIGHT :
309.44
WISWESSER LINE NOTATION :
T56 BOV DHJ D2N2&2 DR

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Intramuscular
SPECIES OBSERVED :
Human
DOSE/DURATION :
1400 ug/kg
TOXIC EFFECTS :
Autonomic Nervous System - smooth muscle relaxant (mechanism undefined, spasmolytic) Behavioral - hallucinations, distorted perceptions Gastrointestinal - other changes
REFERENCE :
JOURAA Journal of Urology. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1917- Volume(issue)/page/year: 54,75,1945

Related Compounds

  • 4-(Difluoromethyl)-3,6-diiodopicolinamide
  • 4-(Difluoromethyl)-3-fluoro-2-nitropyridine
  • 4-(Difluoromethyl)-3-fluoro-5-iodopicolinic acid
  • 4-(Difluoromethyl)-5-fluoro-6-methylpyridin-2-ol
  • (4-(Difluoromethyl)-3-fluoro-6-methylpyridin-2-yl)methanol
  • 2-(4-(Difluoromethyl)-3-fluoro-5-hydroxypyridin-2-yl)acetonitrile
  • 4-(Difluoromethyl)-2-methyl-5-nitropyridin-3-ol
  • (3-(Difluoromethyl)-5-methylphenyl)(pyridin-4-yl)methanone
  • 4-(Difluoromethyl)-3-fluoropicolinoyl chloride
  • (4-(3,5-Dichlorophenyl)pyrimidin-5-yl)methanol
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