N-[1-[(2-methoxyphenyl)methyl]piperidin-4-yl]pyrimidin-2-amine

Names

[ CAS No. ]:
76167-71-0

[ Name ]:
N-[1-[(2-methoxyphenyl)methyl]piperidin-4-yl]pyrimidin-2-amine

Chemical & Physical Properties

[ Density]:
1.187g/cm3

[ Boiling Point ]:
453ºC at 760 mmHg

[ Molecular Formula ]:
C17H22N4O

[ Molecular Weight ]:
298.38300

[ Flash Point ]:
227.7ºC

[ Exact Mass ]:
298.17900

[ PSA ]:
50.28000

[ LogP ]:
2.57260

[ Index of Refraction ]:
1.616

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
UV9285500
CHEMICAL NAME :
Pyrimidine, 2-(1-((o-methoxybenzyl)-4-piperidyl)amino)-
CAS REGISTRY NUMBER :
76167-71-0
LAST UPDATED :
199112
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C17-H22-N4-O
MOLECULAR WEIGHT :
298.43
WISWESSER LINE NOTATION :
T6N CNJ BM- DT6NTJ A1R BO1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
>300 mg/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold Behavioral - changes in motor activity (specific assay) Vascular - relaxation (isolated tissues)
REFERENCE :
FRPSAX Farmaco, Edizione Scientifica. (Casella Postale 227, 27100 Pavia, Italy) V.8-43 1953-88 For publisher information, see FRMCE8 Volume(issue)/page/year: 35,951,1980
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
>300 mg/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold Behavioral - changes in motor activity (specific assay) Vascular - relaxation (isolated tissues)
REFERENCE :
FRPSAX Farmaco, Edizione Scientifica. (Casella Postale 227, 27100 Pavia, Italy) V.8-43 1953-88 For publisher information, see FRMCE8 Volume(issue)/page/year: 35,951,1980

Related Compounds

  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
  • tert-Butyl-DL-alanine
  • 4-amino-N-[2-tert-butyl-1-(tetrahydro-2H-pyran-4-ylmethyl)-1H-benzimidazol-5-yl]-N-ethylbenzenesulfonamide
  • N-[3-(Aminooxy)propyl]-N-butyl-1-butanamine