2-(4-aminophenyl)-3H-benzimidazol-5-amine

Suppliers

Names

[ CAS No. ]:
7621-86-5

[ Name ]:
2-(4-aminophenyl)-3H-benzimidazol-5-amine

[Synonym ]:
2-(4-aminophenyl)-3H-benzimidazol-5-amine

Chemical & Physical Properties

[ Density]:
1.359 g/cm3

[ Boiling Point ]:
545.5ºC at 760 mmHg

[ Molecular Formula ]:
C13H12N4

[ Molecular Weight ]:
224.26100

[ Flash Point ]:
317.6ºC

[ Exact Mass ]:
224.10600

[ PSA ]:
80.72000

[ LogP ]:
3.55670

[ Index of Refraction ]:
1.787

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
DD5421200
CHEMICAL NAME :
1H-Benzimidazol-5-amine, 2-(4-aminophenyl)-
CAS REGISTRY NUMBER :
7621-86-5
LAST UPDATED :
199701
DATA ITEMS CITED :
4
MOLECULAR FORMULA :
C13-H12-N4

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
5 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 43(9),23,1978
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
5500 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 43(9),23,1978 ** OTHER MULTIPLE DOSE TOXICITY DATA **
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
910 mg/kg/26W-I
TOXIC EFFECTS :
Nutritional and Gross Metabolic - weight loss or decreased weight gain Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - dehydrogenases Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - transaminases
REFERENCE :
GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 43(9),23,1978

Safety Information

[ HS Code ]:
2921590090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • benzol-1,2,4-triamindihydrochlorid
  • 4-Aminobenzoic acid
  • 2,4-Dinitroaniline
  • 2'',4'',4-TRINITROBENZANILIDE
  • 6-nitro-2-(4-nitrophenyl)-1H-benzimidazole
  • Benzamide,4-nitro-N-phenyl-
  • 4-Nitrobenzaldehyde
  • 1,2-Diamino-4-nitrobenzene
  • 2'',4'',4-triaminobenzanilide
  • Hydrochloric acid

DownStream

Customs

[ HS Code ]: 2933990090

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Related Compounds

  • 2-(4-aminophenyl)-3H-benzimidazol-5-amine,hydrate
  • Ro 90-7501
  • 4-[6-[[2-(4-aminophenyl)-3H-benzimidazol-5-yl]oxy]-1H-benzimidazol-2-yl]aniline
  • 2-(3-Aminophenyl)-1H-benzo[d]imidazol-6-amine
  • [2-(4-aminophenyl)-3H-benzimidazol-1-ium-5-yl]azanium,dichloride
  • 2-(4-methylpiperazin-1-yl)-3H-benzimidazol-5-amine