D-erythro-Pentonicacid,2,3-dideoxy-3-[2-(3,4,5-trimethoxyphenyl)-1,3-dithian-2-yl]-5-O-(triphenylmethyl)-,g-lactone

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Names

[ CAS No. ]:
76236-33-4

[ Name ]:
D-erythro-Pentonicacid,2,3-dideoxy-3-[2-(3,4,5-trimethoxyphenyl)-1,3-dithian-2-yl]-5-O-(triphenylmethyl)-,g-lactone

[Synonym ]:
(3S,4S)-(+)-3-[2-(3,4,5-trimethoxyphenyl)-1,3-dithiane-2-yl]-4-trityloxymethyl-butan-4-olide
PODOPHYLLOTOXIN,DEGRADED DITHIANE DERIV

Chemical & Physical Properties

[ Density]:
1.232g/cm3

[ Boiling Point ]:
765ºC at 760 mmHg

[ Molecular Formula ]:
C37H38O6S2

[ Molecular Weight ]:
642.82400

[ Flash Point ]:
387.9ºC

[ Exact Mass ]:
642.21100

[ PSA ]:
113.82000

[ LogP ]:
7.67570

[ Index of Refraction ]:
1.611

Synthetic Route

Precursor & DownStream

Precursor

  • S(+)-DIHYDRO-5-TRITYLOXYMETHYL-2(3H)-FURANONE
  • (4S)-(+)-2-phenylseleno-4-trityloxymethyl-butan-4-olide
  • 2-(3,4,5-trimethoxyphenyl)-1,3-dithiane
  • (5S)-5-(trityloxymethyl)-5H-furan-2-one
  • 3,4,5-Trimethoxybenzaldehyde

DownStream

  • (4S,5S)-5-(hydroxymethyl)-4-[(3,4,5-trimethoxyphenyl)methyl]oxolan-2-one
  • (2S,3S,4S)-4-(1,3-benzodioxol-5-ylmethyl)-3-[(3,4,5-trimethoxyphenyl)methyl]pentane-1,2,5-triol

Related Compounds

  • 4-[(5-fluoropyrimidin-2-yl)oxy]-N-(propan-2-yl)piperidine-1-carboxamide
  • N-cyclopentyl-4-[(5-fluoropyrimidin-2-yl)oxy]piperidine-1-carboxamide
  • N-ethyl-4-{[4-(trifluoromethyl)pyrimidin-2-yl]oxy}piperidine-1-carboxamide
  • N-(propan-2-yl)-4-{[4-(trifluoromethyl)pyrimidin-2-yl]oxy}piperidine-1-carboxamide
  • 2-{[1-(3-Chloropyridin-2-yl)piperidin-4-yl]oxy}-5-ethylpyrimidine
  • 3-fluoro-4-methoxy-N-{[4-(morpholin-4-yl)thian-4-yl]methyl}benzamide
  • N-ethyl-4-[(5-fluoropyrimidin-2-yl)oxy]piperidine-1-carboxamide
  • 3-({1-[(Oxolan-2-yl)methyl]piperidin-4-yl}methyl)-3,4-dihydroquinazolin-4-one
  • N-(oxan-4-yl)-3-{[2-(trifluoromethyl)pyridin-4-yl]oxy}azetidine-1-carboxamide
  • 3-[1-(6-Chloroquinazolin-4-yl)pyrrolidin-3-yl]-1,3-oxazolidin-2-one
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