Ethyl 3-ethoxypropanoate

Names

[ CAS No. ]:
763-69-9

[ Name ]:
Ethyl 3-ethoxypropanoate

[Synonym ]:
EINECS 212-112-9
Ethyl 3-ethoxypropionate
Propanoic acid, 3-ethoxy-, ethyl ester
MFCD00051356
Ethyl 3-ethoxypropanoate
Ethyl β-ethoxypropionate

Chemical & Physical Properties

[ Density]:
0.9±0.1 g/cm3

[ Boiling Point ]:
166.2±0.0 °C at 760 mmHg

[ Melting Point ]:
-75 °C

[ Molecular Formula ]:
C₇H₁₄O₃

[ Molecular Weight ]:
146.184

[ Flash Point ]:
52.2±0.0 °C

[ Exact Mass ]:
146.094299

[ PSA ]:
35.53000

[ LogP ]:
1.25

[ Vapour density ]:
5.03 (vs air)

[ Vapour Pressure ]:
1.8±0.3 mmHg at 25°C

[ Index of Refraction ]:
1.408

[ Water Solubility ]:
1.6 g/100 mL (20 ºC)

MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: UF3325000

CHEMICAL NAME :: Propionic acid, 3-ethoxy-, ethyl ester

CAS REGISTRY NUMBER :: 763-69-9

BEILSTEIN REFERENCE NO. :: 1751976

LAST UPDATED :: 199806

DATA ITEMS CITED :: 6

MOLECULAR FORMULA :: C7-H14-O3

MOLECULAR WEIGHT :: 146.21

WISWESSER LINE NOTATION :: 2OV2O2

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

REFERENCE :: 85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986 Volume(issue)/page/year: -,712,1986 ** ACUTE TOXICITY DATA **

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 5 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: AMIHBC AMA Archives of Industrial Hygiene and Occupational Medicine. (Chicago, IL) V.2-10, 1950-54. For publisher information, see AEHLAU. Volume(issue)/page/year: 4,119,1951

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 10 mL/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: AMIHBC AMA Archives of Industrial Hygiene and Occupational Medicine. (Chicago, IL) V.2-10, 1950-54. For publisher information, see AEHLAU. Volume(issue)/page/year: 4,119,1951 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X9259 No. of Facilities: 4669 (estimated) No. of Industries: 40 No. of Occupations: 34 No. of Employees: 42611 (estimated) No. of Female Employees: 5944 (estimated)

Safety Information

[ Symbol ]:

GHS02

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H226

[ Supplemental HS ]:
May form explosive peroxides., Repeated exposure may cause skin dryness or cracking.

[ Precautionary Statements ]:
P210-P403 + P235

[ Hazard Codes ]:
Xi:Irritant;N:Dangerousfortheenvironment;

[ Risk Phrases ]:
R10;R19;R36;R50

[ Safety Phrases ]:
S25

[ RIDADR ]:
UN 3272 3/PG 3

[ WGK Germany ]:
1

[ RTECS ]:
UF3325000

[ Packaging Group ]:
III

[ Hazard Class ]:
3

[ HS Code ]:
2918990090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

Ethanol
Ethyl acrylate TOP1 supplier
diethoxymethane
Hydroxypropionic acid
Acetone
Methyl vinyl ketone
β-Propiolactone
Sodium ethoxide
2-Octanone
ethyl 2- bromo-3-ethoxypropanoate

DownStream

3-Ethoxypropionic Acid
1H-Benzimidazole,2-(2-ethoxyethyl)-
ethyl (Z)-2-(ethoxymethyl)-3-methoxyprop-2-enoate
3t-ethoxy-2-ethoxymethyl-acrylic acid ethyl ester
Ethyl 2-chloropyrimidine-5-carboxylate
Ethyl 2-oxo-1,2-dihydro-5-pyrimidinecarboxylate
Ethyl acrylate TOP1 supplier
2-Amino-pyrimidine-5-carboxylic acid ethyl ester
3-Ethoxy-1-propanol
ETHYL 2-OXO-1,2,3,4-TETRAHYDROPYRIMIDINE-5-CARBOXYLATE

Customs

[ HS Code ]: 2918990090

[ Summary ]:
2918990090. other carboxylic acids with additional oxygen function and their anhydrides, halides, peroxides and peroxyacids; their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Articles

Biodegradation of volatile organic compounds by five fungal species.

Appl. Microbiol. Biotechnol. 58(5) , 684-9, (2002)

Five fungal species, Cladosporium resinae (ATCC 34066), Cladosporium sphaerospermum (ATCC 200384), Exophiala lecanii-corni (CBS 102400), Mucor rouxii (ATCC 44260), and Phanerochaete chrysosporium (ATC...

The metabolism and disposition of ethyl 3-ethoxypropionate in the rat.

Xenobiotica 20(10) , 989-97, (1990)

1. The metabolism and disposition of ethyl 3-ethoxypropionate (EEP) in male Sprague-Dawley rats was studied following single oral gavage at 150 or 1500 mg/kg. The 14C-EEP was rapidly absorbed at both ...

J. Photopolym. Sci. Technol. 16 , 335-345, (2003)

ethyl 3-(2-chlorophenyl)imino-3-ethoxypropanoate
ethyl 3-[(2-chloro-5-nitrophenyl)imino]-3-ethoxypropionate
ethyl 2- bromo-3-ethoxypropanoate
ethyl 3-hydroxy-3-methyl-1,2,3,6-tetrahydropyridine-1-carboxylate
ethyl 3-anthracen-2-ylpropanoate
ethyl 3-methylcyclohepta-2,4,6-triene-1-carboxylate
2-[1-(naphthalen-2-ylsulfonyl)pyrrolidin-2-yl]-1H-benzimidazole
N-(4-bromophenyl)-2-[(2S,11aS)-2-hydroxy-5,11-dioxo-2,3,11,11a-tetrahydro-1H-pyrrolo[2,1-c][1,4]benzodiazepin-10(5H)-yl]acetamide
5-bromo-N~3~-[2-(5-fluoro-1H-indol-3-yl)ethyl]nicotinamide
N-(butan-2-yl)-5-chloro-2-(methylsulfonyl)pyrimidine-4-carboxamide
4-[4-oxo-1,2,3-benzotriazin-3(4H)-yl]-N~1~-(4-pyridylmethyl)butanamide
N-(3,4-dimethoxyphenyl)phenazine-1-carboxamide
N-{[3-(4-methoxyphenyl)-1,2,4-oxadiazol-5-yl]methyl}-3-(4-oxo-3(4H)-quinazolinyl)propanamide
8,9-dimethyl-7-(4-methyl-2-pyridinyl)-2-(4-pyridinyl)-7H-pyrrolo[3,2-e][1,2,4]triazolo[1,5-c]pyrimidine
2-[4-oxo-1,2,3-benzotriazin-3(4H)-yl]-N~1~-(2-oxo-2H-chromen-6-yl)acetamide
5-ethyl-N-(2-{[1-(1H-indol-3-yl)propan-2-yl]amino}-2-oxoethyl)-8-oxo-5,8-dihydro[1,3]dioxolo[4,5-g]quinoline-7-carboxamide

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