2-Amino-1,3-octadecanediol

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Names

[ CAS No. ]:
764-22-7

[ Name ]:
2-Amino-1,3-octadecanediol

[Synonym ]:
erythro-Sphinganine
D-erythro-Sphinganine
2-Aminooctadecane-1,3-diol
Dihydro-C18-sphingosine
(2S,3R)-2-aminooctadecane-1,3-diol
D-erythro-2-Amino-1,3-octadecanediol
2-Amino-1,3-dihydroxyoctadecane
DL-erythro-2-Amino-1,3-octadecanediol
1,3-Octadecanediol, 2-amino-
2-Amino-1,3-octadecanediol
Octadephinganine
D-erythro-C18-Dihydrosphingosine
C18-Dihydrosphingosine
Dihydrosphingosine
DL-erythro-1,3-Dihydroxy-2-aminooctadecane

Chemical & Physical Properties

[ Density]:
0.9±0.1 g/cm3

[ Boiling Point ]:
446.2±25.0 °C at 760 mmHg

[ Melting Point ]:
70-72ºC

[ Molecular Formula ]:
C18H39NO2

[ Molecular Weight ]:
301.508

[ Flash Point ]:
223.7±23.2 °C

[ Exact Mass ]:
301.298065

[ PSA ]:
66.48000

[ LogP ]:
6.27

[ Vapour Pressure ]:
0.0±2.4 mmHg at 25°C

[ Index of Refraction ]:
1.478

[ Storage condition ]:
-20°C

MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
NONH for all modes of transport

Synthetic Route

Precursor & DownStream

Precursor

  • D-erythro-Sphingosine
  • (2S,3R,4E)-2-azido-1,3-dibenzyloxyoctadeca-4-ene
  • N-[(1S,2R)-2-Hydroxy-1-(hydroxyMethyl)heptadecyl]carbamic Acid 1,1-Dimethylethyl Ester
  • (R)-N-((2S,3R)-1,3-dihydroxyoctadecan-2-yl)-2-methylpropane-2-sulfinamide
  • dibenzyl 1-((2S,3R,E)-1-(benzyloxy)-3-hydroxyoctadec-5-en-2-yl)hydrazine-1,2-dicarboxylate
  • (2S,3R)-2-amino-1,3-dihydroxyoctadec-4-yne
  • (2R,3R)-2-amino-3-hydroxyoctadecanoic acid
  • (2S,3R)-2-[(tert-butoxycarbonyl)amino]-1,2-O-N-isopropylideneoctadecane-1,3-diol

DownStream

  • Formaldehyde
  • Formic Acid
  • 1-hexadecanal
  • Ammonia
  • Palmitic acid
  • Pentadecanoic acid
  • N-acetoyl-D-erythro-sphinganine
  • symbioramide

Articles

Chemical genetics reveals a complex functional ground state of neural stem cells.

Nat. Chem. Biol. 3(5) , 268-273, (2007)

The identification of self-renewing and multipotent neural stem cells (NSCs) in the mammalian brain holds promise for the treatment of neurological diseases and has yielded new insight into brain canc...

Lipidomic profiling reveals significant alterations in lipid biochemistry in hypothyroid rat cerebellum and the therapeutic effects of Sini decoction.

J. Ethnopharmacol. 159 , 262-73, (2014)

Hypothyroidism is known to be closely associated with lipid metabolism. Although our previous serum and urine metabonomics studies have provided some clues about the molecular mechanism of hypothyroid...

Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.

Nat. Chem. Biol. 5 , 765-71, (2009)

Studies of gene function and molecular mechanisms in Plasmodium falciparum are hampered by difficulties in characterizing and measuring phenotypic differences between individual parasites. We screened...


More Articles


Related Compounds

  • 2-Amino-1,3-octadecanediol
  • (2R,3R)-2-Amino-1,3-octadecanediol
  • L-threo sphinganine,2S,3S) L-threo-2-amino-1,3-octadecanediol
  • DL-erythro-1,3-Dihydroxy-2-aminooctadecane,DL-erythro-2-Amino-1,3-octadecanediol,DL-Sphinganine
  • 2-amino-1-(3-bromophenyl)ethanone
  • 2-amino-1,3-propanediol oxalate
  • Methyl 2'-amino-6'-ethyl-7'-methyl-2,5'-dioxo-1-(prop-2-en-1-yl)-1,2,5',6'-tetrahydrospiro[indole-3,4'-pyrano[3,2-c]pyridine]-3'-carboxylate
  • Methyl 2'-amino-1-ethyl-6',7'-dimethyl-2,5'-dioxo-1,2,5',6'-tetrahydrospiro[indole-3,4'-pyrano[3,2-c]pyridine]-3'-carboxylate
  • ethyl 2-amino-6-ethyl-7,11-dimethyl-5,12-dioxospiro[6-hydro-4H-pyrano[3,2-c]py ridine-4,3'-indoline]-3-carboxylate
  • Methyl 2'-amino-1-ethyl-7'-methyl-2,5'-dioxo-6'-((tetrahydrofuran-2-yl)methyl)-5',6'-dihydrospiro[indoline-3,4'-pyrano[3,2-c]pyridine]-3'-carboxylate
  • methyl 2-amino-11-(carbamoylmethyl)-7-methyl-5,12-dioxospiro[6-hydro-4H-pyrano [3,2-c]pyridine-4,3'-indoline]-3-carboxylate
  • methyl 2-amino-6,11-diethyl-7-methyl-5,12-dioxospiro[6-hydro-4H-pyrano[3,2-c]p yridine-4,3'-indoline]-3-carboxylate
  • (14aS,26aR)-2,3,13,14,14a,15,26,26a-Octahydro-22,30-dimethoxy-14-methyl-1H-4,6:16,19-dietheno-21,25-metheno-12H-[1,3]dioxolo[4,5-g]pyrido[2 inverted exclamation marka,3 inverted exclamation marka:17,18][1,10]dioxacycloeicosino[2,3,4-ij]isoquinoline
  • Ethyl 1-allyl-2'-amino-6',7'-dimethyl-2,5'-dioxo-5',6'-dihydrospiro[indoline-3,4'-pyrano[3,2-c]pyridine]-3'-carboxylate
  • methyl 2-amino-1'-[(4-chlorophenyl)methyl]-7-methyl-2',5-dioxospiro[6H-pyrano[3,2-c]pyridine-4,3'-indole]-3-carboxylate
  • methyl 2'-amino-6'-(furan-2-ylmethyl)-7'-methyl-2,5'-dioxospiro[1H-indole-3,4'-pyrano[3,2-c]pyridine]-3'-carboxylate
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