promethazine sulfoxide

Suppliers

Names

[ Name ]:
promethazine sulfoxide

[Synonym ]:
Promethazine sulfoxide
10-(2-dimethyl-aminopropyl)-phenothiazine sulphoxide
10-(2-(Dimethylamino)propyl)-10H-phenothiazine 5-oxide
Romergan sulfoxide
Promethazine 5-Oxide
Promethiazine sulfoxide
Promethazine 5-Sulfoxide
promethasine sulfoxide

Chemical & Physical Properties

[ Density]:
1.27g/cm3

[ Boiling Point ]:
461.6ºC at 760 mmHg

[ Molecular Formula ]:
C₁₇H₂₀N₂OS

[ Molecular Weight ]:
300.41900

[ Flash Point ]:
233ºC

[ Exact Mass ]:
300.13000

[ PSA ]:
42.76000

[ LogP ]:
4.18560

[ Index of Refraction ]:
1.678

[ Storage condition ]:
Refrigerator

Safety Information

[ HS Code ]:
2934999090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2934999090

[ Summary ]:
2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

[Simultaneous determination of chlorpromazine and promethazine and their main metabolites by capillary electrophoresis with electrochemiluminescence].

Se Pu 30(9) , 938-42, (2012)

Based on the phenomenon that each of chlorpromazine (CPZ), promethazine (PMZ), chlorpromazine sulfoxide (CPZSO) and promethazine sulfoxide (PMZSO) could enhance the electrochemiluminescence (ECL) inte...

Horseradish peroxidase-catalyzed sulfoxidation of promethazine and properties of promethazine sulfoxide.

Free Radic. Biol. Med. 20(6) , 807-11, (1996)

Promethazine sulfoxide was obtained with a quantitative yield in a horse radish peroxidase-catalyzed reaction of promethazine and hydrogen peroxide and was also prepared by direct chemical synthesis. ...

A peroxidase-catalyzed sulfoxidation of promethazine.

Free Radic. Res. 27(5) , 501-4, (1997)

Lactoperoxidase, when incubated with increasing amounts of promethazine (P) and promethazine sulfoxide (PO) catalyzes the formation of promethazine sulfoxide accompanied by oxygen consumption. An inte...