2-Amino-3-(4-hydroxyphenyl)propanehydrazide

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
490.8±40.0 °C at 760 mmHg

[ Melting Point ]:
196-198 °C(lit.)

[ Molecular Formula ]:
C₉H₁₃N₃O₂

[ Molecular Weight ]:
195.218

[ Flash Point ]:
250.6±27.3 °C

[ Exact Mass ]:
195.100784

[ PSA ]:
101.37000

[ LogP ]:
-0.91

[ Vapour Pressure ]:
0.0±1.3 mmHg at 25°C

[ Index of Refraction ]:
1.620

Click to get detail MSDS

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H317-H319

[ Precautionary Statements ]:
P280-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Faceshields;Gloves

[ Hazard Codes ]:
Xi: Irritant;

[ Risk Phrases ]:
R36

[ Safety Phrases ]:
S26-S36/37

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2928000090

Click to get detail synthetic route

Precursor

DownStream

[ HS Code ]: 2928000090

[ Summary ]:
2928000090 other organic derivatives of hydrazine or of hydroxylamine VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:20.0%

Design and evaluation of hydroxamate derivatives as metal-mediated inhibitors of a protein tyrosine kinase.

J. Med. Chem. 49 , 7532-9, (2006)

Protein tyrosine kinases use two Mg(2+) ions as cofactors in catalysis, one as the ATP-Mg complex (M1) and the other as an essential activator (M2). The M2-binding site has high affinity for transitio...

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