2,1,3-Benzothiadiazol-4-amine

Suppliers

Names

[ CAS No. ]:
767-64-6

[ Name ]:
2,1,3-Benzothiadiazol-4-amine

[Synonym ]:
2,1,3-Benzothiadiazol-4-amine
EINECS 212-186-2
MFCD00005810
4-Amino-2,1,3-benzothiadiazole

Chemical & Physical Properties

[ Density]:
1.5±0.1 g/cm3

[ Boiling Point ]:
303.0±15.0 °C at 760 mmHg

[ Melting Point ]:
67-69 °C(lit.)

[ Molecular Formula ]:
C6H5N3S

[ Molecular Weight ]:
151.189

[ Flash Point ]:
137.1±20.4 °C

[ Exact Mass ]:
151.020416

[ PSA ]:
80.04000

[ LogP ]:
0.70

[ Vapour Pressure ]:
0.0±0.6 mmHg at 25°C

[ Index of Refraction ]:
1.785

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
DK9950000
CHEMICAL NAME :
2,1,3-Benzothiadiazole, 4-amino-
CAS REGISTRY NUMBER :
767-64-6
BEILSTEIN REFERENCE NO. :
0003551
LAST UPDATED :
199612
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C6-H5-N3-S
MOLECULAR WEIGHT :
151.20
WISWESSER LINE NOTATION :
T56 BNSNJ FZ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
200 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
PCJOAU Pharmaceutical Chemistry Journal (English Translation). Translation of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013) No.1- 1967- Volume(issue)/page/year: 12,1277,1978
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
180 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. (Aberdeen Proving Ground, MD 21010) Volume(issue)/page/year: NX#03368

Safety Information

[ Hazard Codes ]:
Xn:Harmful;

[ Risk Phrases ]:
R20/21/22;R36/37/38

[ Safety Phrases ]:
S22-S26-S36/37/39

[ RIDADR ]:
UN 2811 6.1/PG 3

[ WGK Germany ]:
3

[ RTECS ]:
DK9950000

[ Packaging Group ]:
III

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 4-nitro-2,1,3-benzothiadiazole
  • Acetamide,N-2,1,3-benzothiadiazol-4-yl-
  • 1-(TERT-BUTOXYCARBONYL)-4-OXOPYRROLIDINE-2-CARBOXYLICACID
  • 3,5-Dichlorophenyl isocyanate
  • N-Boc-4-oxo-L-proline
  • Benzo[c][1,2,5]thiadiazol-4(1H)-one
  • 2,1,3-Benzothiadiazole
  • o-Phenylenediamine
  • 3-Nitro-1,2-benzenediamine

DownStream

  • 2,1,3-benzothiadiazole-4,7-diamine
  • 2,1,3-BENZOTHIADIAZOL-4-YL ISOTHIOCYANATE
  • 1,3-dihydro-2,1,3-benzothiadiazole-4,7-dione
  • 2,1,3-Benzothiadiazol-4-amine,5,7-dichloro-
  • 4-Methoxy-2,1,3-benzothiadiazole
  • Acetamide,N-2,1,3-benzothiadiazol-4-yl-
  • 4-BROMO-2,1,3-BENZOTHIADIAZOLE
  • 4-bromo-5,7-dinitro-2,1,3-benzothiadiazole

Related Compounds

  • 5-nitro-2,1,3-benzothiadiazol-4-amine
  • 5-Ethoxy-2,1,3-benzothiadiazol-4-amine
  • 7-chloro-2,1,3-benzothiadiazol-4-amine
  • 6-methyl-2,1,3-benzothiadiazol-4-amine
  • 5-chloro-2,1,3-benzothiadiazol-4-amine
  • N,N-dimethyl-2,1,3-benzothiadiazol-4-amine
  • E6Clv6G2RR
  • 4-(3-Chloro-phenylsulfanyl)benzoic acid
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 1-((5-Oxo-1-(p-tolyl)pyrrolidin-3-yl)methyl)-3-(m-tolyl)urea
  • 1-((3-(4-Chlorophenyl)-2-oxooxazolidin-5-yl)methyl)-3-(4-ethoxyphenyl)urea
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • 2,2-Diethylpiperazine