L-Glutamic acid,N-[4-[[(2,4-diaminopyrido[3,2-d]pyrimidin-6-yl)methyl]methylamino]benzoyl]-

Suppliers

Names

[ CAS No. ]:
76822-62-3

[ Name ]:
L-Glutamic acid,N-[4-[[(2,4-diaminopyrido[3,2-d]pyrimidin-6-yl)methyl]methylamino]benzoyl]-

[Synonym ]:
8-Deazamethotrexate
L-Glutamic acid,4-diaminopyrido[3,2-d]pyrimidin-6-yl)methyl]methylamino]benzoyl]
N-[4-[(2,4-diaminopyrido[3,2-d]pyrimidin-6-ylmethyl)methylamino]benzoyl]-L-glutamic acid

Chemical & Physical Properties

[ Density]:
1.499g/cm3

[ Molecular Formula ]:
C21H23N7O5

[ Molecular Weight ]:
453.45100

[ Exact Mass ]:
453.17600

[ PSA ]:
197.65000

[ LogP ]:
2.42670

[ Index of Refraction ]:
1.731

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • diethyl N-[4-[(2,4-diaminopyrido[3,2-d]pyrimidin-6-ylmethyl)methylamino]benzoyl]-L-glutamate
  • Pyrido(3,2-d)pyrimidine-6-methanol, 2,4-dichloro-, acetate (ester)
  • (2,4-dioxo-1H-pyrido[3,2-d]pyrimidin-6-yl)methyl acetate
  • (2,4-diaminopyrido[3,2-d]pyrimidin-6-yl)methanol
  • 6-(bromomethyl)pyrido[3,2-d]pyrimidine-2,4-diamine
  • 2,4-Dioxo-6-methylpyrido[3,2-d]pyrimidine 5-Oxide
  • Diethyl N-[4-(methylamino)benzoyl]-L-glutamate

DownStream