2,3,5,6-tetrafluorothiophenol

Names

[ CAS No. ]:
769-40-4

[ Name ]:
2,3,5,6-tetrafluorothiophenol

[Synonym ]:
MFCD00004829
2,3,5,6-tetrafluorobenzenethiol
EINECS 212-210-1

Chemical & Physical Properties

[ Density]:
1.53

[ Boiling Point ]:
152-153 °C(lit.)

[ Molecular Formula ]:
C₆H₂F₄S

[ Molecular Weight ]:
182.13900

[ Flash Point ]:
119 °F

[ Exact Mass ]:
181.98100

[ PSA ]:
38.80000

[ LogP ]:
2.53170

[ Index of Refraction ]:
n20/D 1.4865(lit.)

[ Storage condition ]:
Flammables area

MSDS

Safety Information

[ Symbol ]:

GHS02, GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H226-H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
Xi:Irritant;

[ Risk Phrases ]:
R10;R36/37/38

[ Safety Phrases ]:
S16-S26-S36/37/39

[ RIDADR ]:
UN 3336 3/PG 3

[ WGK Germany ]:
3

[ Packaging Group ]:
III

[ Hazard Class ]:
3

[ HS Code ]:
2930909090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

Pentafluorobenzene
1,2,4,5-Tetrafluorobenzene

DownStream

(2,3,5,6-tetrafluorophenyl) thiohypochlorite
1-bromo-2,3,5,6-tetrafluorbenzene
1-Bromo-2,3,4,5,6-pentafluorobenzene
3-Chloro-1,2,4,5-tetrafluorobenzene
Benzoic acid,2,3,5,6-tetrafluoro-4-mercapto-

Customs

[ HS Code ]: 2930909090

[ Summary ]:
2930909090. other organo-sulphur compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Articles

A gas-chromatographic assay method for busulfan with sensitivity for test dose therapeutic monitoring.

J. Pharm. Biomed. Anal. 13(9) , 1073-8, (1995)

A gas-chromatographic assay method was developed and validated for determination of busulfan in human plasma for test dose therapeutic drug monitoring. Busulfan and the internal standard (1,6-bis-(met...

Gas-chromatographic analysis of busulfan for therapeutic drug monitoring.

Cancer Chemother. Pharmacol. 32(2) , 137-42, (1993)

The development and validation of a gas chromatographic assay method for determination of total and free busulfan concentrations in human plasma for pharmacokinetic studies is reported. 1,6-Bis(methan...

Quantification of busulfan in plasma by gas chromatography-mass spectrometry following derivatization with tetrafluorothiophenol.

J. Chromatogr. B. Biomed. Sci. Appl. 709(1) , 47-56, (1998)

A specific and highly sensitive method has been developed for the determination of busulfan in plasma by gas chromatography-mass spectrometry using a deuterium-labeled busulfan (busulfan-d8) as intern...

2,3,5,6-TETRAFLUOROTHIOPHENOL
4-Methyl-2,3,5,6-tetrafluorothiophenol
4-chloro-2,3,5,6-tetrafluorothiophenol
4-trifluoromethyl-2,3,5,6-tetrafluorothiophenol
2,3,5,6-tetramethylcyclohex-2-enone
2,3,5,6,-tetrahydronaphtho[1,2-b:4,3-b']bis[1,4]oxathiin-2,7-dione
2-{N-benzyl-2-[4-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)phenyl]propanamido}acetic acid
2-cyclopropyl-2-[8-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)octanamido]acetic acid
(2S)-2-{2-[2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)cyclopentyl]acetamido}propanoic acid
2-{N-ethyl-3-[({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)methyl]-4-methylpentanamido}acetic acid
5-[N-ethyl-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-2-methylpropanamido]pentanoic acid
2-[4-(dimethylamino)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)butanamido]-3-methoxy-2-methylpropanoic acid
4-[4-(dimethylamino)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)butanamido]-3-methoxybutanoic acid
2-[3-cyclobutyl-3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)propanoyl]-2-azabicyclo[2.1.1]hexane-5-carboxylic acid
1-[5-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-2-methylpentanoyl]-1,2,3,6-tetrahydropyridine-4-carboxylic acid
8-[(2S)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)pentanoyl]-8-azabicyclo[3.2.1]octane-3-carboxylic acid