N-[(4-chlorophenyl)carbamoyl]-2-[(6-nitro-4-oxo-quinazolin-3-yl)methyl amino]acetamide

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Names

[ CAS No. ]:
76979-57-2

[ Name ]:
N-[(4-chlorophenyl)carbamoyl]-2-[(6-nitro-4-oxo-quinazolin-3-yl)methyl amino]acetamide

[Synonym ]:
ls-8644

Chemical & Physical Properties

[ Density]:
1.57g/cm3

[ Molecular Formula ]:
C18H15ClN6O5

[ Molecular Weight ]:
430.80200

[ Exact Mass ]:
430.07900

[ PSA ]:
154.43000

[ LogP ]:
3.68090

[ Index of Refraction ]:
1.712

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
AB5832000
CHEMICAL NAME :
Acetamide, N-(((4-chlorophenyl)amino)carbonyl)-2-(((6-nitro-4-ox o-3(4H)-quinazolinyl) methyl) amino)-
CAS REGISTRY NUMBER :
76979-57-2
LAST UPDATED :
199612
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C18-H15-Cl-N6-O5
MOLECULAR WEIGHT :
430.84

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Mammal - species unspecified
DOSE/DURATION :
>800 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
INDRBA Indian Drugs. (Indian Drugs Manufacturers' Assoc., 102B, Poonam Chambers, Dr. A. B. Rd., Worli, Bombay 400 018, India) V.1- 1963- Volume(issue)/page/year: 20,94,1982

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 1-(2-chloroacetyl)-3-(4-chlorophenyl)urea
  • 3-aminomethyl-6-nitro-3H-quinazolin-4-one

DownStream

Related Compounds

  • 4-methyl-4-p-tolyl-4,5,6,7-tetrahydro-3H-imidazo[4,5-c]pyridine
  • 3-(6-Chloro-2-methoxyacridin-9-ylamino)phenol
  • 1-(Quinolin-2-ylmethyl)pyrazol-3-amine
  • 1-(2-Chloro-ethyl)-3-[3-(8-isopropyl-5-methyl-6-oxo-5,6,7,8-tetrahydro-pteridin-2-ylamino)-5-methylsulfonyl-phenyl]urea
  • 3-(Methylsulfonyl)-5-trifluoromethyl-phenylamine
  • 4-(1,3-Benzothiazol-2-yl)-1-[4-(pyridin-2-yl)piperazin-1-yl]butan-1-one
  • 3-Bromo-2,5-diphenylthiophene
  • 4-(3-Aminopropyl)-2,6-dimethylphenol
  • [4-[(E)-2-phenylethenyl]sulfonylpiperazin-1-yl]-(5-pyridin-3-yl-1,2-oxazol-3-yl)methanone
  • Tert-butyl 1-(5-iodopyridin-2-yl)piperidin-4-ylcarbamate