2,4(1H,3H)-Pyridinedione,3,3-diethyl-

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Names

[ CAS No. ]:
77-04-3

[ Name ]:
2,4(1H,3H)-Pyridinedione,3,3-diethyl-

[Synonym ]:
Pyrithyldion
Presidon
Pyridion
Persedon
EINECS 201-000-5
Didropyridine
3,3-Diaethyl-1H-pyridin-2,4-dion
Persidon
3,3-Diethyl-2,4-dioxo-1,2,3,4-tetrahydro-pyridin
Dihydroprylone
Benedorm
Prezidon
pyrithyldione
Didropyridin

Chemical & Physical Properties

[ Density]:
1.029g/cm3

[ Boiling Point ]:
187-189ºC (14 mmHg)

[ Molecular Formula ]:
C9H13NO2

[ Molecular Weight ]:
167.20500

[ Flash Point ]:
147.8ºC

[ Exact Mass ]:
167.09500

[ PSA ]:
46.17000

[ LogP ]:
1.33420

[ Index of Refraction ]:
1.464

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
UT2810530
CHEMICAL NAME :
2,4(1H,3H)-Pyridinedione, 3,3-diethyl-
CAS REGISTRY NUMBER :
77-04-3
BEILSTEIN REFERENCE NO. :
0131564
LAST UPDATED :
199612
DATA ITEMS CITED :
3
MOLECULAR FORMULA :
C9-H13-N-O2
MOLECULAR WEIGHT :
167.23
WISWESSER LINE NOTATION :
T6MV DV CHJ C2 C2

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
780 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
APPBDI Acta Physiologica et Pharmacologica Bulgarica. (Izdatelstvo na Bulgarskata Akademiya na Naukite, ul. Akad. G. Bonchev, 1113 Sofia, Bulgaria) V.1- 1974- Volume(issue)/page/year: 10(3),29,1984
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
660 mg/kg
TOXIC EFFECTS :
Behavioral - anticonvulsant Behavioral - sleep Behavioral - changes in motor activity (specific assay)
REFERENCE :
DBANAD Doklady Bolgarskoi Akademii Nauk. (Hemus, Blvd. Russki 6, Sofia, Bulgaria) V.1- 1948- Volume(issue)/page/year: 34,135,1981
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
980 mg/kg
TOXIC EFFECTS :
Behavioral - anticonvulsant Behavioral - sleep Behavioral - changes in motor activity (specific assay)
REFERENCE :
DBANAD Doklady Bolgarskoi Akademii Nauk. (Hemus, Blvd. Russki 6, Sofia, Bulgaria) V.1- 1948- Volume(issue)/page/year: 34,135,1981

Safety Information

[ Hazard Codes ]:
Xn

[ Risk Phrases ]:
R20/21

[ Safety Phrases ]:
S23

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • ethyl 5-amino-2,2-diethyl-3-oxopent-4-enoate
  • ethyl 2,2-diethylacetoacetate

DownStream

  • 3,3-diethyl-5-(hydroxymethyl)pyridine-2,4(1H,3H-dione
  • 3,3-Diethyl-1-methyl-2,4(1H,3H)-pyridinedione
  • 3,3-diethyl-5-methylpiperidine-2,4-dione
  • Piperidione
  • Ethypicone

Related Compounds

  • 2,4(1H,3H)-Pyridinedione,3,3-diethyl-1-(4-nitrobenzoyl)
  • 2,4(1H,3H)-Pyridinedione,3,3-diethyl-1-(3-nitrobenzoyl)
  • 2,4(1H,3H)-Pyridinedione,3,3-diethyl-1-(3,5-dimethoxybenzoyl)
  • 2,4(1H,3H)-Pyridinedione,3,3-diethyl-1-(3,4,5-trimethoxybenzoyl)
  • 2,4(1H,3H)-Pyridinedione,3,3-diethyl-1-((4-morpholinylamino)methyl)
  • 2,4(1H,3H)-Pyridinedione,3,3-diethyl-5-(hydroxymethyl)-1-(2-(4-morpholinyl)ethyl)