Chlorphenoxamine

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Names

[ CAS No. ]:
77-38-3

[ Name ]:
Chlorphenoxamine

[Synonym ]:
Clorfenossamina [DCIT]
2-(1-(4-Chlorophenyl)-1-phenylethoxy)-N,N-dimethylethanamine
Chlorphenoxamine [INN:BAN]
Clorfenoxamina [INN-Spanish]
{2-[1-(4-Chlor-phenyl)-1-phenyl-aethoxy]-aethyl}-dimethyl-amin
{2-[1-(4-chloro-phenyl)-1-phenyl-ethoxy]-ethyl}-dimethyl-amine
Chlorphenoxaminum [INN-Latin]
Contristamine
Chlorphenoxamine

Chemical & Physical Properties

[ Density]:
1.093g/cm3

[ Boiling Point ]:
383.7ºC at 760 mmHg

[ Molecular Formula ]:
C18H22ClNO

[ Molecular Weight ]:
303.82600

[ Flash Point ]:
185.9ºC

[ Exact Mass ]:
303.13900

[ PSA ]:
12.47000

[ LogP ]:
4.18170

[ Index of Refraction ]:
1.551

[ Storage condition ]:
2-8°C

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
KR3185000
CHEMICAL NAME :
Ethylamine, 2-(1-(p-chlorophenyl)-1-phenylethoxy)-N,N-dimethyl-
CAS REGISTRY NUMBER :
77-38-3
BEILSTEIN REFERENCE NO. :
2057618
LAST UPDATED :
199709
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C18-H22-Cl-N-O
MOLECULAR WEIGHT :
303.86
WISWESSER LINE NOTATION :
GR DX1&R&O2N1&1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
376 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 7,237,1957
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
167 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 7,237,1957

Safety Information

[ Hazard Codes ]:
Xi

[ HS Code ]:
2922199090

Synthetic Route

Precursor & DownStream

Precursor

  • 4-Chlorobenzoyl chloride
  • Phenyllithium
  • 4-Chlorobenzophenone
  • 1-(4-chlorophenyl)-1-phenylethanol
  • 2-Chloroethyldimethylamine

DownStream

Customs

[ HS Code ]: 2922199090

[ Summary ]:
2922199090. other amino-alcohols, other than those containing more than one kind of oxygen function, their ethers and esters; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%


Related Compounds

  • Chlorphenoxamine
  • Chlorphenoxamine HCl
  • (3S, 5S)-5-Amino-1-benzyl-piperidin-3-ol hydrochloride
  • 1-(2-(4-Isothiocyanatophenoxy)ethyl)pyrrolidine
  • (S)-6-Methyl-2-oxa-5,8-diazaspiro[3.5]nonane oxalate
  • 4-[[[1-(4-Methoxyphenyl)ethyl]amino]carbonyl]-1H-pyrazole-1-propanoic acid
  • 8,8-Difluoro-2-azabicyclo[5.1.0]octane 2,2,2-trifluoroacetate
  • 2-Methoxy-2-methylbutanoic acid
  • 5-Chloro-6-fluoro-3,4-dimethoxypicolinaldehyde
  • 4-[[[1-(1-Ethyl-3-methyl-1H-pyrazol-4-yl)ethyl]amino]carbonyl]-1H-pyrazole-1-propanoic acid
  • (S)-1-(3,5-Difluorophenyl)-2,2,2-trifluoroethanamine hcl
  • 3-[[2-(2-Cyclopenten-1-yl)acetyl]amino]benzamide
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