Monoethylglycinexylidide

Suppliers

Names

[ CAS No. ]:
7728-40-7

[ Name ]:
Monoethylglycinexylidide

[Synonym ]:
monoethylglycine-2,6-xylidide
monoethyl glycine xylidide
MEGX
N-Ethylglycinexylidide
ethylaminoacet-2,6-xylidide
L 86
Ethylglycylxylidide
desmethyllidocaine
2-ethylamino-2',6'-dimethylacetanilide
Norlidocaine
2-Ethylamino-2,6-acetoxylidine
2-Ethylamino-2',6'-acetoxylidide
N-(2,6-dimethylphenyl)-2-(ethylamino)acetamide

Chemical & Physical Properties

[ Density]:
1.047g/cm3

[ Boiling Point ]:
335.6ºC at 760 mmHg

[ Melting Point ]:
242-245ºC

[ Molecular Formula ]:
C12H18N2O

[ Molecular Weight ]:
206.28

[ Flash Point ]:
127.8ºC

[ Exact Mass ]:
206.14200

[ PSA ]:
41.13000

[ LogP ]:
2.31530

[ Index of Refraction ]:
1.553

[ Storage condition ]:
2-8°C

MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
AN7740000
CHEMICAL NAME :
2',6'-Acetoxylidide, 2-(ethylamino)-
CAS REGISTRY NUMBER :
7728-40-7
BEILSTEIN REFERENCE NO. :
2417108
LAST UPDATED :
199612
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C12-H18-N2-O
MOLECULAR WEIGHT :
206.32
WISWESSER LINE NOTATION :
2M1MVR B1 F1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
234 mg/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold
REFERENCE :
JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 179,580,1971

Safety Information

[ Symbol ]:

GHS06

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H301

[ Precautionary Statements ]:
P301 + P310

[ RIDADR ]:
UN 2811 6.1 / PGIII

[ RTECS ]:
AN7740000

[ HS Code ]:
2924299090

Synthetic Route

Precursor & DownStream

Precursor

  • Ethylamine
  • 2-Chloro-N-(2,6-dimethylphenyl)acetamide
  • Lidocaine hydrochloride
  • Lidocaine
  • 2,6-xylidine

DownStream

  • Glycinexylidide
  • 3-Hydroxy-N-desethyl Lidocaine
  • 3-(2,6-dimethylphenyl)-1-ethyl-2-methylimidazolidin-4-one

Customs

[ HS Code ]: 2924299090

[ Summary ]:
2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

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Related Compounds

  • Monoethylglycinexylidide-d6
  • Monoethylglycinexylidide-d6 hydrochloride
  • [2H5]-Norlidocaine,[2H5]-Monoethylglycinexylidide