Azidomethyl Phenyl Sulfide

Names

[ CAS No. ]:
77422-70-9

[ Name ]:
Azidomethyl Phenyl Sulfide

[Synonym ]:
MFCD00009700
azidomethylsulfanylbenzene

Chemical & Physical Properties

[ Density]:
1.168 g/mL at 25ºC(lit.)

[ Boiling Point ]:
104-105ºC 5 mm Hg(lit.)

[ Molecular Formula ]:
C₇H₇N₃S

[ Molecular Weight ]:
165.21600

[ Flash Point ]:
226 °F

[ Exact Mass ]:
165.03600

[ PSA ]:
75.05000

[ LogP ]:
2.49926

[ Index of Refraction ]:
n20/D 1.5904(lit.)

[ Storage condition ]:
Refrigerator

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;half-mask respirator (US);multi-purpose combination respirator cartridge (US)

[ Risk Phrases ]:
44

[ Safety Phrases ]:
36

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

2-[(Dimethylamino)methyl]aniline
NCC-149
NITROMETHYL PHENYL SULFONE
2,6-Dimethoxyaniline
Benzenamine, 2,6-dimethoxy-4-[(phenylthio)methyl]-
1-amino-N-(phenylsulfanylmethyl)cyclohex-3-ene-1-carboxamide
Acetic acid,1-(2-phenylethyl)-2-[[(phenylthio)methyl]imino]hydrazide
N-(phenylsulfanylmethyl)benzamide

Articles

Regioselective Sequential Modification of Chitosan via Azide-Alkyne Click Reaction: Synthesis, Characterization, and Antimicrobial Activity of Chitosan Derivatives and Nanoparticles.

PLoS ONE 10 , e0123084, (2015)

Recently, the attention of researchers has been drawn toward the synthesis of chitosan derivatives and their nanoparticles with enhanced antimicrobial activities. In this study, chitosan derivatives w...

High-throughput chemical modification of oligonucleotides for systematic structure-activity relationship evaluation.

Bioconjug. Chem. 25(12) , 2222-32, (2014)

Chemical modification of siRNA is achieved in a high-throughput manner (96-well plate format) by copper catalyzed azide-alkyne cycloadditions. This transformation can be performed in one synthetic ope...

Most anti-BrdU antibodies react with 2'-deoxy-5-ethynyluridine -- the method for the effective suppression of this cross-reactivity.

PLoS ONE 7(12) , e51679, (2012)

5-Bromo-2'-deoxyuridine (BrdU) and 2'-deoxy-5-ethynyluridine (EdU) are widely used as markers of replicated DNA. While BrdU is detected using antibodies, the click reaction typically with fluorescent ...