3-Bromo-4-methylaniline

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Names

[ CAS No. ]:
7745-91-7

[ Name ]:
3-Bromo-4-methylaniline

[Synonym ]:
EINECS 231-807-8
9CI.3-Bromo-p-toluidine
3-Bromo-4-methylaniline
3-Bromo-1,4-toluidine
Benzenamine, 3-bromo-4-methyl-
3-BROMO-PARA-TOLUIDINE
3-bromo-4-methylphenylamine
p-Toluidine,3-bromo
4-AMINO-2-BROMOTOLUENE
3-BROMO-P-TOLUIDINE
3-bromo-4-methyl-aniline
3-bromo-4-methyl-benzenamin
MFCD00134176
3-bromo-p-toluidin
3-bromo-N,N,4-trimethylaniline

Chemical & Physical Properties

[ Density]:
1.5±0.1 g/cm3

[ Boiling Point ]:
258.3±20.0 °C at 760 mmHg

[ Melting Point ]:
27-30 °C(lit.)

[ Molecular Formula ]:
C7H8BrN

[ Molecular Weight ]:
186.049

[ Flash Point ]:
110.0±21.8 °C

[ Exact Mass ]:
184.984009

[ PSA ]:
26.02000

[ LogP ]:
2.56

[ Vapour Pressure ]:
0.0±0.5 mmHg at 25°C

[ Index of Refraction ]:
1.609

[ Storage condition ]:
Refrigerator

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
XU4375000
CHEMICAL NAME :
p-Toluidine, 3-bromo-
CAS REGISTRY NUMBER :
7745-91-7
BEILSTEIN REFERENCE NO. :
1562057
LAST UPDATED :
199707
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C7-H8-Br-N
MOLECULAR WEIGHT :
186.07
WISWESSER LINE NOTATION :
ZR CE D1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
180 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
ARTODN Archives of Toxicology. (Springer-Verlag, Heidelberger Pl. 3, D-1000 Berlin 33, Fed. Rep. Ger.) V.32- 1974- Volume(issue)/page/year: 54,275,1983
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Bird - wild bird species
DOSE/DURATION :
1900 ug/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 21,315,1972

Safety Information

[ Symbol ]:

GHS06

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H301-H315-H319-H335

[ Precautionary Statements ]:
P261-P301 + P310-P305 + P351 + P338

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;Gloves;type P2 (EN 143) respirator cartridges

[ Hazard Codes ]:
T:Toxic

[ Risk Phrases ]:
R25;R36/37/38

[ Safety Phrases ]:
S26-S45-S37/39-S28A

[ RIDADR ]:
UN 2811 6.1/PG 3

[ WGK Germany ]:
3

[ RTECS ]:
XU4375000

[ Packaging Group ]:
III

[ Hazard Class ]:
6.1

[ HS Code ]:
2921430090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 2-Bromo-4-nitrotoluene
  • p-Toluidine
  • 4-Bromo-5-methyl-2-nitroaniline
  • 2-Methyl-5-nitroaniline
  • Sulfuric acid
  • Bromine
  • Hydrochloric acid

DownStream

  • 5-Methoxy-2-methylbenzoic acid
  • 3-Bromo-4-methylbenzonitrile
  • 3-Bromo-4-methylphenol
  • 2,4-Dibromotoluene
  • 5-Amino-2-methylbenzonitrile
  • N-(3-bromo-4-methylphenyl)-2-hydroxyiminoacetamide
  • 2-Bromo-4-iodotoluene
  • 2-Bromo-4-methylbenzaldehyde
  • 8-Bromo-6-methylquinoline
  • 3-bromo-4-methylbenzenesulfonamide

Customs

[ HS Code ]: 2921430090

[ Summary ]:
HS:2921430090 toluidines and their derivatives; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

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Related Compounds

  • 3-Bromo-4-methoxy-5-methylaniline
  • 3-bromo-4-methoxy-2-methylaniline
  • 3-Bromo-4-iodo-5-methylaniline
  • 3-Bromo-4-fluoro-5-methylaniline
  • 3-bromo-4-isopropyl-2-methyl-aniline
  • (3-bromo-4-methylphenyl)[(4-methoxy-1-naphthyl)methylene]amine