KM 11060

Suppliers

Names

[ CAS No. ]:
774549-97-2

[ Name ]:
KM 11060

[Synonym ]:
7-Chloro-4-{4-[(4-chlorophenyl)sulfonyl]-1-piperazinyl}quinoline
Quinoline, 7-chloro-4-[4-[(4-chlorophenyl)sulfonyl]-1-piperazinyl]-
7-chloro-4-{4-[(4-chlorophenyl)sulfonyl]piperazin-1-yl}quinoline
7-chloro-4-{4-[(4-chlorophenyl)sulfonyl]piperazino}quinoline
KM 11060
KM11060

Chemical & Physical Properties

[ Density]:
1.5±0.1 g/cm3

[ Boiling Point ]:
607.3±65.0 °C at 760 mmHg

[ Molecular Formula ]:
C19H17Cl2N3O2S

[ Molecular Weight ]:
422.328

[ Flash Point ]:
321.1±34.3 °C

[ Exact Mass ]:
421.041840

[ PSA ]:
61.89000

[ LogP ]:
4.19

[ Vapour Pressure ]:
0.0±1.7 mmHg at 25°C

[ Index of Refraction ]:
1.676

[ Storage condition ]:
2-8℃

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS06

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H301

[ Precautionary Statements ]:
P301 + P310

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;Gloves;type P2 (EN 143) respirator cartridges

[ RIDADR ]:
UN 2811 6.1 / PGIII

[ HS Code ]:
2935009090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 4-Chlorobenzenesulfonyl chloride
  • 7-Chloro-4-(piperazin-1-yl)quinoline
  • 4,7-Dichloroquinoline

DownStream

Customs

[ HS Code ]: 2935009090

[ Summary ]:
2935009090 other sulphonamides VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:35.0%

Articles

Important role of platelets in modulating endotoxin-induced lung inflammation in CFTR-deficient mice.

PLoS ONE 8 , e82683, (2013)

Mutation of CFTR (cystic fibrosis transmembrane conductance regulator) leads to cystic fibrosis (CF). Patients with CF develop abnormalities of blood platelets and recurrent lung inflammation. However...


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Related Compounds

  • km 09440
  • km 07648
  • KM-233
  • [(8R,9S,13S,14S,17S)-17-[2-[4-[4-(2-chloroethylamino)phenyl]butanoyloxy]acetyl]oxy-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-3-yl] benzoate
  • [(2S,3S,4S,5R,6S)-6-[2-hexadecanoyloxy-3-[(5E,8E,11E,14E,17E)-icosa-5,8,11,14,17-pentaenoyl]oxypropoxy]-3,4,5-trihydroxyoxan-2-yl]methanesulfonic acid
  • hemicellulase
  • 8-Fluoro-1,6-naphthyridin-5(6H)-one
  • cis-Hex-4-enylmagnesium chloride
  • 2-[Amino(cyclopropyl)methyl]-4-bromo-3,5-dimethylphenol
  • 2-(1-Amino-2-methylpropyl)-6-bromo-4-methylphenol
  • 6-Amino-3-pentyl-1,2,4-triazolo[3,4-f][1,2,4]triazin-8(5H)-one
  • 5-(Cyclohexylmethyl)-2-pyridinamine
  • 1-(2-Bromo-5-chlorophenyl)-2,2-difluoroethan-1-amine
  • 2,2-Difluoro-1-(3-methoxy-4-methylphenyl)ethan-1-amine
  • 1-(4-Bromo-3-fluorophenyl)-2,2-difluoroethan-1-amine
  • Methyl 2-amino-2-(3-bromo-2-hydroxyphenyl)acetate
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