5'-hydroxypiroxicam

Names

[ CAS No. ]:
77459-78-0

[ Name ]:
5'-hydroxypiroxicam

[Synonym ]:
5'-Hydroxypiroxicam
HYDROXY PIROXICAM METABOLITE

Chemical & Physical Properties

[ Density]:
1.636g/cm3

[ Boiling Point ]:
627.1ºC at 760 mmHg

[ Molecular Formula ]:
C₁₅H₁₃N₃O₅S

[ Molecular Weight ]:
347.34600

[ Flash Point ]:
333.1ºC

[ Exact Mass ]:
347.05800

[ PSA ]:
131.70000

[ LogP ]:
2.95480

[ Index of Refraction ]:
1.729

MSDS

Safety Information

[ Symbol ]:

GHS06

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H301

[ Precautionary Statements ]:
P301 + P310

[ Hazard Codes ]:
Xn

[ Risk Phrases ]:
22

[ RIDADR ]:
UN 2811 6.1 / PGIII

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

2-Bromo-3-methoxypyridine
2-Bromo-3-methoxy-6-nitropyridine
N-(5'-methoxy-2'-pyridyl)-4-hydroxy-2-methyl-2H-1,2-benzothiazine-3-carboxamide 1,1-dioxide
2-Amino-5-methoxypyridine

DownStream

Articles

[The binding of oxicam derivatives to human serum albumin].

Arzneimittelforschung 38(8) , 1089-92, (1988)

The binding characteristics of several oxicam derivatives (tenoxicam, 4-hydroxy-2-methyl-N-phenyl-2H-1,2-benzothiazixine-3- carboxamide-1,1-dioxide (CP 14,304), 4-hydroxy-2-methyl-N-2-(3-methyl)-pyrid...

High-performance liquid chromatographic analysis of piroxicam and its major metabolite 5'-hydroxypiroxicam in human plasma and urine.

J. Chromatogr. A. 382 , 382-8, (1986)

Determination of piroxicam and its major metabolites in the plasma, urine and bile of humans by high-performance liquid chromatography.

J. Chromatogr. A. 576(1) , 121-8, (1992)

A simple and sensitive liquid chromatographic method with ultraviolet detection is described for the determination of the nonsteroidal anti-inflammatory drug piroxicam and its major metabolites in hum...

5'-Hydroxypiroxicam
5'-O-dimethoxytrityl-2'-O-(4-methoxybenzyl)uridine
5'-O-(L-valyl)-5-fluorouridine HCl
5',6-Diformyl-2,2',3-trimethoxydiphenylether
5'-bromo-3',4'-dihydro-1'H-spiro[imidazolidine-4,2'-naphthalene]-2,5-dione
5'-Chloromethyl-5'-hydroxy-2-methyl-tetrahydro-[2,2']bifuranyl-5-one
6-Bromo-2,2-dimethylthiochroman-4-one
(4,5,6-Trimethyl-2-oxo-1(2H)-pyrimidinyl)acetic acid
2-{[11-(hydroxymethyl)-14-methyl-5-(3-methylphenyl)-2-oxa-4,6,13-triazatricyclo[8.4.0.0^{3,8}]tetradeca-1(10),3(8),4,6,11,13-hexaen-7-yl]sulfanyl}-N-(4-methylphenyl)acetamide
Ethyl 4-({[(6-thien-2-ylpyridazin-3-yl)thio]acetyl}amino)benzoate
N-(3,5-dimethylphenyl)-2-((6-(pyridin-2-yl)pyridazin-3-yl)thio)acetamide
1-(5-Bromopyridin-2-yl)-2-(4-methyl-1H-imidazol-1-yl)ethanone
1-(Propylsulfanyl)propane-2-thiol
(1Z)-(3,4,9-trimethyl-7H-furo[2,3-f]chromen-7-ylidene)hydrazine
[[[4-(Methoxymethylene)cyclohexyl]oxy]methyl]benzene
Ethyl 7-methylpyrazolo[1,5-a]pyrimidine-3-carboxylate

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