MeIQx
Suppliers
Names
[ CAS No. ]:
77500-04-0
[ Name ]:
MeIQx
[Synonym ]:
3,8-dimethyl-3H-imidazo<quinoxalin-2-amine
3,8-dimethylimidazo[4,5-f]quinoxalin-2-amine
8-MeIQX
8-Methyl-IQX
Chemical & Physical Properties
[ Density]:
1.47 g/cm3
[ Boiling Point ]:
458.4ºC at 760mmHg
[ Melting Point ]:
> 300ºC
[ Molecular Formula ]:
C11H11N5
[ Molecular Weight ]:
213.23900
[ Exact Mass ]:
213.10100
[ PSA ]:
69.62000
[ LogP ]:
1.98830
[ Index of Refraction ]:
1.776
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- NJ5925500
- CHEMICAL NAME :
- 3H-Imidazo(4,5-f)quinoxaline, 2-amino-3,8-dimethyl-
- CAS REGISTRY NUMBER :
- 77500-04-0
- LAST UPDATED :
- 199806
- DATA ITEMS CITED :
- 27
- MOLECULAR FORMULA :
- C11-H11-N5
- MOLECULAR WEIGHT :
- 213.27
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 8580 mg/kg/61W-C
- TOXIC EFFECTS :
- Tumorigenic - Carcinogenic by RTECS criteria Sense Organs and Special Senses (Ear) - effect, not otherwise specified Liver - tumors
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 42336 mg/kg/84W-C
- TOXIC EFFECTS :
- Tumorigenic - Carcinogenic by RTECS criteria Liver - tumors Blood - leukemia
- TYPE OF TEST :
- Specific locus test
- TYPE OF TEST :
- Morphological transformation
- TYPE OF TEST :
- DNA adduct
- TYPE OF TEST :
- Cytogenetic analysis
- TYPE OF TEST :
- Sister chromatid exchange
- TYPE OF TEST :
- DNA adduct
- TYPE OF TEST :
- DNA damage
- TYPE OF TEST :
- Sister chromatid exchange
MUTATION DATA
- TYPE OF TEST :
- Mutation in mammalian somatic cells
- TEST SYSTEM :
- Rodent - hamster Lung
- DOSE/DURATION :
- 50 mg/L
- REFERENCE :
- MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 118,91,1983 *** REVIEWS *** IARC Cancer Review:Animal Sufficient Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 56,211,1993 IARC Cancer Review:Animal Inadequate Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 40,283,1986 IARC Cancer Review:Human No Adequate Data IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 40,283,1986 IARC Cancer Review:Human Inadequate Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 56,211,1993 IARC Cancer Review:Group 2B IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 56,211,1993
Safety Information
[ Hazard Codes ]:
T
[ RTECS ]:
NJ5925500
[ HS Code ]:
2933990090
Synthetic Route
Customs
[ HS Code ]: 2933990090
[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%