methyl (E)-7-[1-(benzenesulfonyl)-5-dimethylamino-3-(dimethyl-tert-butyl-silyl)oxy-2-[(E)-3-(dimethyl-tert-butyl-silyl)oxyoct-1-enyl]cyclopentyl]hept-5-enoate

Suppliers

Names

[ CAS No. ]:
77506-98-0

[ Name ]:
methyl (E)-7-[1-(benzenesulfonyl)-5-dimethylamino-3-(dimethyl-tert-butyl-silyl)oxy-2-[(E)-3-(dimethyl-tert-butyl-silyl)oxyoct-1-enyl]cyclopentyl]hept-5-enoate

[Synonym ]:
Methyl (5Z,13E,8R,9S,11R,12S,15S)-11,15-Bis(tert-butyldimethylsiloxy)-9-(dimethylamino)-8-(phenylsulfonyl)-5,13-prostadienoate
methyl (4-tert-butoxycarbonylaminophenoxy)acetate
METHYL 2-(4-((TERT-BUTOXYCARBONYL)AMINO)PHENOXY)ACETATE

Chemical & Physical Properties

[ Density]:
1.03g/cm3

[ Boiling Point ]:
715.8ºC at 760 mmHg

[ Molecular Formula ]:
C41H73NO6SSi2

[ Molecular Weight ]:
764.25700

[ Flash Point ]:
386.7ºC

[ Exact Mass ]:
763.47000

[ PSA ]:
90.52000

[ LogP ]:
11.43690

[ Index of Refraction ]:
1.512

Synthetic Route

Precursor & DownStream

Precursor

  • methyl 7-bromohept-5-enoate
  • Phenylacetyl-triphenylsilan
  • (1S,4R)-cis-4-(tert-Butyldimethylsiloxy)-1-(dimethylamino)-2-(phenylsulfonyl)-2-cyclopentene
  • methyl 7-iodohept-5-enoate
  • (1E,3S)-3-t-butyldimethylsilyloxy-1-lithio-octane

DownStream

  • Dinoprostone
  • Prostaglandin A2 methyl ester
  • Prostaglandin E2 methyl ester
  • PROSTAGLANDIN A2