dihydromevinolin

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Names

[ CAS No. ]:
77517-29-4

[ Name ]:
dihydromevinolin

Chemical & Physical Properties

[ Density]:
1.1g/cm3

[ Boiling Point ]:
534.8ºC at 760 mmHg

[ Molecular Formula ]:
C24H38O5

[ Molecular Weight ]:
406.55600

[ Flash Point ]:
174.5ºC

[ Exact Mass ]:
406.27200

[ PSA ]:
72.83000

[ LogP ]:
4.27540

[ Index of Refraction ]:
1.52

Safety Information

[ RIDADR ]:
NONH for all modes of transport

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • methyl (1S,2S,4aR,6S,8S,8aS,3'R,2''S)-3'-(tert-butyldimethylsiloxy)-7'-[1,2,4a,5,6,7,8,8a-octahydro-2,6-dimethyl-8-[(2''-methylbutyryl)oxy]-1-naphthalenyl]-5'-oxohept-6'-enoate

DownStream

Articles

Total synthesis and biological evaluation of structural analogues of compactin and dihydromevinolin.

J. Med. Chem. 30(10) , 1858-73, (1987)

The full experimental details for the total synthesis of (+)-compactin and 19 structural analogues are reported. We have evaluated three classes of analogues as inhibitors of 3-hydroxy-3-methylglutary...

Dihydromevinolin, a potent hypocholesterolemic metabolite produced by Aspergillus terreus.

J. Antibiot. 34(5) , 507-12, (1981)

A new, potent hypocholesterolemic agent is produced by cultures of Aspergillus terreus. The isolation of the compound and its characterization as 4a,5-dihydromevinolin containing a trans-fused octahyd...


More Articles

Related Compounds

  • 1-(3-Bromo-5-methylthiophen-2-yl)prop-2-en-1-ol
  • 2-Bromo-1-(3,5-difluoropyridin-4-yl)ethan-1-ol
  • 1-(3-Bromo-2,2-dimethylpropyl)-5-fluoro-2-methoxy-4-methylbenzene
  • 4-(2-Bromopropyl)-2-chloro-1-nitrobenzene
  • 3-(4-Bromo-5-methylthiophen-2-yl)propan-1-ol
  • 4-(1-bromo-2-methylpropan-2-yl)-3-tert-butyl-1H-pyrazole
  • 1-Bromo-3-(4-nitrobut-3-en-1-yl)benzene
  • 3-(3-bromoprop-1-en-2-yl)-4,5,6,7-tetrahydro-1H-indazole
  • 1-(3-Bromo-4-methylthiophen-2-yl)cyclobutane-1-carboxylic acid
  • 1-(4-Bromo-2-methylphenyl)-3-oxocyclobutane-1-carboxylic acid
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