formylpiperazine

Names

[ Name ]:
formylpiperazine

[Synonym ]:
N-Formylpiperazine
piperazine-1-carbaldehyde
EINECS 231-813-0
1-Piperazinecarbaldehyde
1-Piperazinecarboxaldehyde
formylpiperazine
MFCD00005963

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
291.7±0.0 °C at 760 mmHg

[ Melting Point ]:
88-91

[ Molecular Formula ]:
C₅H₁₀N₂O

[ Molecular Weight ]:
114.146

[ Flash Point ]:
101.7±0.0 °C

[ Exact Mass ]:
114.079315

[ PSA ]:
32.34000

[ LogP ]:
-1.26

[ Vapour Pressure ]:
0.0±0.6 mmHg at 25°C

[ Index of Refraction ]:
1.552

[ Storage condition ]:
2-8°C

MSDS

Safety Information

[ Symbol ]:

GHS05, GHS07

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H302-H315-H318-H335

[ Precautionary Statements ]:
P261-P280-P305 + P351 + P338

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
Xn:Harmful;

[ Risk Phrases ]:
R22;R37/38;R41

[ Safety Phrases ]:
S26-S36

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
2

[ HS Code ]:
2933599090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

Piperazine
methyl formate
carbon monoxide
N,N-Dimethylformamide
Chloroform
piperazine-oxalate
1,4-Piperazinedicarbaldehyde
Ethyl formate
(Z)-Methanimidic acid

DownStream

Methyl undecanoate
1-Piperazinecarboxaldehyde,4-butyl-(8CI,9CI)
1-PIPERAZINECARBOXYLIC ACID,4-FORMYL-,1,1-DIMETHYLETHYL ESTER
1-Piperazinecarboxaldehyde,4-(3-hydroxypropyl)-(9CI)
4-Chlorophenol
4-Nitrothiophenol
4-benzoyl-1-piperazinecarboxaldehyde
1-(4-chloro-benzoyl)-4-formyl-piperazine
1-(4-methyl-benzoyl)-4-formyl-piperazine
4-Fluorophenol

Customs

[ HS Code ]: 2933599090

[ Summary ]:
2933599090. other compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

Synthesis and receptor binding assay of indolin-2-one derivatives as dopamine D4 receptor ligands.

Pharmazie 70 , 511-4, (2015)

Five indolin-2-one derivatives bearing piperazinylbutyl side chains attached to the amide nitrogen were synthesized from 2-indolinone. 1-(4-Bromobutyl)-indolin-2-one was reacted with 1-piperazinecarbo...

Infrared and Raman spectra, conformational stability and vibrational assignment of 1-formylpiperazine.

Spectrochim. Acta. A. Mol. Biomol. Spectrosc. 118 , 1113-1120, (2014)

Infrared and Raman spectra of 1-formylpiperazine (1-fp) have been recorded in the region of 4000-50 cm(-1). The conformational analysis, optimized geometric parameters, normal mode frequencies and cor...

1-Formylpiperazine and related compounds. Horrom BW, et al.

J. Am. Chem. Soc. 77(3) , 753-754, (1955)

1-Boc-4-formylpiperazine
4-ethyl-1-formylpiperazine
1-Allyl-4-formylpiperazine
4-Farnesyl-1-formylpiperazine
4-formylpiperazinecarboxamidine
1-Benzhydryl-4-formylpiperazine
3-Amino-N-methyl-4-methylamino-benzamide
tert-Butyl [2-({2-amino-4-[(cyclopentylamino)carbonyl]phenyl}amino)ethyl]carbamate
[(3R)-1-[[(2R,3R,4R,5S,6R)-5-hydroxy-4-[(3R)-3-hydroxyhexadecanoyl]oxy-2-[[(2R,3S,4R,5R)-3-hydroxy-5-[[(3R)-3-hydroxyhexadecanoyl]amino]-4-[(3R)-3-hydroxyhexadecanoyl]oxy-6-oxooxan-2-yl]methoxy]-6-(hydroxymethyl)oxan-3-yl]amino]-1-oxohexadecan-3-yl] 27-hydroxyoctacosanoate
tert-butyl N-(3-aminopropyl)-N-cycloheptylcarbamate
N-(1-cyanocyclopentyl)-2-{[(2,3-dihydro-1,4-benzodioxin-2-yl)methyl](ethyl)amino}acetamide
1-{4H,5H,6H,7H-thieno[3,2-c]pyridine-5-carbonyl}piperidine-3-carboxylic acid
2-Phenylethyl 1-[(3-methyl-5-isoxazolyl)carbonyl]-3-oxo-2-piperazineacetate
1-(1,2,3,4-tetrahydroquinolin-1-yl)-2-{4H,5H,6H,7H-thieno[3,2-c]pyridin-5-yl}ethan-1-one
4-(Methylamino)benzamide hydrochloride
Parent of Heme O

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