Enoximone

Suppliers

Names

[ CAS No. ]:
77671-31-9

[ Name ]:
Enoximone

[Synonym ]:
Fenoximone
Enoximonum [Latin]
2H-Imidazol-2-one, 1,3-dihydro-4-methyl-5-(4-(methylthio)benzoyl)-
5-methyl-4-(4-(methylthio)benzoyl)-1H-imidazol-2(3H)-one
[14C]-Enoximone
2H-Imidazol-2-one, 1,3-dihydro-4-methyl-5-[4-(methylthio)benzoyl]-
4-Methyl-5-[4-(methylsulfanyl)benzoyl]-1,3-dihydro-2H-imidazol-2-one
Enoximona
MFCD00867130
Perfane
Enoximonum
Enoximona [Spanish]
1,3-dihydro-4-methyl-5-[4-(methylthio)benzoyl]-2H-imidazol-2-one
Enoximone
Perfan

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Melting Point ]:
255-258°C

[ Molecular Formula ]:
C12H12N2O2S

[ Molecular Weight ]:
248.301

[ Exact Mass ]:
248.061951

[ PSA ]:
91.02000

[ LogP ]:
3.72

[ Appearance of Characters ]:
solid | light yellow

[ Index of Refraction ]:
1.645

[ Storage condition ]:
Store at +4°C

[ Water Solubility ]:
DMSO: 28 mg/mL, soluble

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;half-mask respirator (US);multi-purpose combination respirator cartridge (US)

[ RIDADR ]:
3249

[ WGK Germany ]:
3

[ Packaging Group ]:
III

[ Hazard Class ]:
6.1(b)

[ HS Code ]:
2933290090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 1,3-Dihydro-4-methyl-2H-imidazol-2-one
  • 4-Methylthio benzoic acid
  • 4-methylsulfanylbenzoyl chloride
  • 4'-Fluoroacetophenone
  • 4-(Methylthio)acetophenone

DownStream

Customs

[ HS Code ]: 2933290090

[ Summary ]:
2933290090. other compounds containing an unfused imidazole ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

Recovery of heart function in children with acute severe heart failure.

Transplantation 85(7) , 975-9, (2008)

The prognosis of acute heart failure is such that many children are considered for transplantation. Recovery of severe heart failure in a proportion of patients diagnosed with either dilated cardiomyo...

Effects of enoximone on peripheral and central chemoreflex responses in humans.

Am. J. Physiol. Heart Circ. Physiol. 294(1) , H322-9, (2008)

cAMP plays an important role in peripheral chemoreflex function in animals. We tested the hypothesis that the phosphodiesterase inhibitor and inotropic medication enoximone increases peripheral chemor...

[Tolerance of enoximone in patients with heart failure].

Z. Kardiol. 80 Suppl 4 , 93-7, (1991)

Enoximone, a new phosphodiesterase-inhibitor with positive inotropic and vasodilating activities is available for intravenous use in patients with severe heart failure. A review of the current knowled...


More Articles

Related Compounds

  • enoximone sulfoxide
  • 4-Ethyl-3-methyl-6-[(1-{[1,3]thiazolo[4,5-c]pyridin-2-yl}piperidin-4-yl)methoxy]pyridazine
  • 3-[1-(6-bromo-1,3-benzothiazol-2-yl)piperidin-4-yl]-4-cyclopropyl-1-methyl-4,5-dihydro-1H-1,2,4-triazol-5-one
  • 3-fluoro-4-methoxy-N-(4-methylpyridin-3-yl)benzamide
  • 2-(Cyclobutylmethyl)-6-(4-fluorophenyl)-2,3-dihydropyridazin-3-one
  • 1-(2,5-Dimethylfuran-3-carbonyl)-4-(fluoromethyl)piperidine
  • 1-(4-Fluorophenyl)-3-(prop-2-en-1-ylsulfanyl)-1,2-dihydropyrazin-2-one
  • 5-[4-(fluoromethyl)piperidine-1-carbonyl]-1H-indole
  • 6-[4-(Fluoromethyl)piperidine-1-carbonyl]quinoxaline
  • N-ethyl-2-(4-{thieno[3,2-c]pyridin-4-yl}piperazin-1-yl)pyrimidin-4-amine
  • 2-(ethylsulfanyl)-6-methyl-3-propyl-3H,4H,5H-pyrrolo[3,2-d]pyrimidin-4-one
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