thallium(i) chloride

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Names

[ CAS No. ]:
7791-12-0

[ Name ]:
thallium(i) chloride

[Synonym ]:
Thallium(I) Chloride
EINECS 232-241-4
MFCD00011274
chlorothallium

Chemical & Physical Properties

[ Density]:
7 g/mL at 25 °C(lit.)

[ Boiling Point ]:
720 °C

[ Melting Point ]:
430 °C(lit.)

[ Molecular Formula ]:
ClTl

[ Molecular Weight ]:
239.83600

[ Exact Mass ]:
239.94300

[ LogP ]:
0.68950

[ Vapour Pressure ]:
10 mm Hg ( 517 °C)

[ Index of Refraction ]:
2.247

MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
XG4200000
CHEMICAL NAME :
Thallium(I) chloride
CAS REGISTRY NUMBER :
7791-12-0
LAST UPDATED :
199712
DATA ITEMS CITED :
30
MOLECULAR FORMULA :
Cl-Tl
MOLECULAR WEIGHT :
239.82
WISWESSER LINE NOTATION :
TL G

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
6900 ug/kg
TOXIC EFFECTS :
Brain and Coverings - encephalitis Gastrointestinal - other changes Skin and Appendages - hair
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
24 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
23982 ug/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
150 mg/kg
TOXIC EFFECTS :
Gastrointestinal - hypermotility, diarrhea Kidney, Ureter, Bladder - other changes
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
50 mg/kg/10D-I
TOXIC EFFECTS :
Lungs, Thorax, or Respiration - fibrosis, focal (pneumoconiosis) Skin and Appendages - hair Related to Chronic Data - death
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
60 mg/kg/10D-I
TOXIC EFFECTS :
Lungs, Thorax, or Respiration - fibrosis, focal (pneumoconiosis) Skin and Appendages - hair Related to Chronic Data - death
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
DOSE :
30 mg/kg
SEX/DURATION :
female 6-15 day(s) after conception
TOXIC EFFECTS :
Reproductive - Specific Developmental Abnormalities - musculoskeletal system

MUTATION DATA

TYPE OF TEST :
Morphological transformation
TEST SYSTEM :
Rodent - hamster Embryo
DOSE/DURATION :
100 umol/L
REFERENCE :
CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year: 39,193,1979 *** REVIEWS *** ACGIH TLV-TWA 0.1 mg(Tl)/m3 (skin) DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year: TLV/BEI,1997 *** U.S. STANDARDS AND REGULATIONS *** OSHA PEL (Gen Indu):8H TWA 0.1 mg(Tl)/m3 (skin) CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1910.1000,1994 OSHA PEL (Construc):8H TWA 0.1 mg(Tl)/m3 (skin) CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1926.55,1994 OSHA PEL (Shipyard):8H TWA 0.1 mg(Tl)/m3 (skin) CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1915.1000,1993 OSHA PEL (Fed Cont):8H TWA 0.1 mg(Tl)/m3 (skin) CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 41,50-204.50,1994 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-AUSTRALIA:TWA 0.1 mg(Tl)/m3;Skin JAN 1993 OEL-BELGIUM:TWA 0.1 mg(Tl)/m3;Skin JAN 1993 OEL-DENMARK:TWA 0.1 mg(Tl)/m3;Skin JAN 1993 OEL-FINLAND:TWA 0.1 mg(Tl)/m3;Skin JAN 1993 OEL-FRANCE:TWA 0.1 mg(Tl)/m3 JAN 1993 OEL-GERMANY:TWA 0.1 mg(Tl)/m3 JAN 1993 OEL-THE NETHERLANDS:TWA 0.1 mg(Tl)/m3;Skin JAN 1993 OEL-THE PHILIPPINES:TWA 0.1 mg(Tl)/m3;Skin JAN 1993 OEL-SWITZERLAND:TWA 0.1 mg(Tl)/m3;Skin JAN 1993 OEL-THAILAND:TWA 0.1 mg(Tl)/m3 JAN 1993 OEL-TURKEY:TWA 0.1 mg(Tl)/m3;Skin JAN 1993 OEL-UNITED KINGDOM:TWA 0.1 mg(Tl)/m3;Skin JAN 1993 OEL IN BULGARIA, COLOMBIA, JORDAN, KOREA check ACGIH TLV OEL IN NEW ZEALAND, SINGAPORE, VIETNAM check ACGIH TLV

Safety Information

[ Symbol ]:

GHS06, GHS08, GHS09

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H300 + H330-H373-H411

[ Precautionary Statements ]:
P260-P264-P273-P284-P301 + P310-P310

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges

[ Hazard Codes ]:
T+,N

[ Risk Phrases ]:
R26/28

[ Safety Phrases ]:
S13-S28-S45-S61

[ RIDADR ]:
UN 1707 6.1/PG 2

[ WGK Germany ]:
3

[ RTECS ]:
XG4200000

[ Packaging Group ]:
II

[ Hazard Class ]:
6.1

Articles

Comments on contaminants in thallous (201Tl) chloride.

Eur. J. Nucl. Med. Mol. Imaging 35(12) , 2339, (2008)

Detection of perineural tumor invasion of the head and neck: clinical use of thallium-201 SPECT/CT image fusion.

Clin. Nucl. Med. 33(8) , 567-70, (2008)

Novel method for quantitative evaluation of cardiac amyloidosis using (201)TlCl and (99m)Tc-PYP SPECT.

Ann. Nucl. Med. 26(8) , 634-43, (2012)

The degree of myocardial technetium-(99m)-pyrophosphate ((99m)Tc-PYP) accumulation in cardiac amyloidosis is conventionally evaluated by the PYP score. This method involves qualitative visual evaluati...


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Related Compounds

  • (201Tl)thallium(I) chloride
  • thallium(I) 4-methoxyphenolate
  • thallium (i) perchlorate
  • thallium(i) hexafluoroacetylacetonate
  • THALLIUM(I)NITRITE
  • thallium(I) isopropanethiolate
  • N-(2-Methoxyethyl)-1-[4-(2,4,6-trimethylbenzenesulfonamido)benzoyl]piperidine-4-carboxamide
  • O-Ethyl (2-chloropyridin-4-yl)methylsulfanylmethanethioate
  • Ethyl 1-(4-fluorophenyl)-5-hydroxypyrazole-4-carboxylate
  • Benzyl 4-(2-chlorophenyl)-4-hydroxypiperidine-1-carboxylate
  • (3-Phenoxypropyl)hydrazine hydrochloride
  • [2-(Benzyloxy)ethyl]hydrazine hydrochloride
  • 1-(4-bromophenyl)-3-methyl-1H-pyrazole-4-carboxylic acid
  • 1H-Pyrazole-4-carboxylic acid, 1-(2,4-difluorophenyl)-3-methyl-
  • 3-(2-aminoethoxy)-N-cyclohexylbenzamide
  • Methyl hydrogen (aminomethyl)phosphonate
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