1-Ethynyl-1-cyclohexanol

Suppliers

Names

[ CAS No. ]:
78-27-3

[ Name ]:
1-Ethynyl-1-cyclohexanol

[Synonym ]:
1-ethynyl-cyclohexano
MFCD00003858
1-ethynyl-cyclohexan-1-ol
1-Ethynyl-1-cyclohexano
Cyclohexanol, 1-ethynyl-
1-Ethin-1-cyclohexanol
1-Ethynyl-1-cyclohexanol
Ethynylcyclohexanol
1-Ethynyl-1-cyclohex
1-Ethynylcyclohexanol
1-ETHYNYLCYCLOHEXANOL-1
1-ethynyl-1-hydroxycyclohexane
EINECS 201-100-9

Chemical & Physical Properties

[ Density]:
1.0±0.1 g/cm3

[ Boiling Point ]:
174.0±0.0 °C at 760 mmHg

[ Melting Point ]:
30-33 °C(lit.)

[ Molecular Formula ]:
C8H12O

[ Molecular Weight ]:
124.180

[ Flash Point ]:
62.8±0.0 °C

[ Exact Mass ]:
124.088814

[ PSA ]:
20.23000

[ LogP ]:
1.73

[ Vapour Pressure ]:
0.4±0.7 mmHg at 25°C

[ Index of Refraction ]:
1.494

[ Storage condition ]:
2-8°C

[ Water Solubility ]:
10 g/L (20 ºC)

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
GV9100000
CHEMICAL NAME :
Cyclohexanol, 1-ethynyl-
CAS REGISTRY NUMBER :
78-27-3
BEILSTEIN REFERENCE NO. :
0471404
LAST UPDATED :
199710
DATA ITEMS CITED :
6
MOLECULAR FORMULA :
C8-H12-O
MOLECULAR WEIGHT :
124.20
WISWESSER LINE NOTATION :
L6TJ AQ A1UU1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
Open irritation test
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rabbit
REFERENCE :
AIHAAP American Industrial Hygiene Association Journal. (AIHA, 475 Wolf Ledges Pkwy., Akron, OH 44311) V.19- 1958- Volume(issue)/page/year: 23,95,1962 ** ACUTE TOXICITY DATA **
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
600 uL/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
AIHAAP American Industrial Hygiene Association Journal. (AIHA, 475 Wolf Ledges Pkwy., Akron, OH 44311) V.19- 1958- Volume(issue)/page/year: 23,95,1962
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
500 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 5,161,1955
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
1 mL/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
AIHAAP American Industrial Hygiene Association Journal. (AIHA, 475 Wolf Ledges Pkwy., Akron, OH 44311) V.19- 1958- Volume(issue)/page/year: 23,95,1962

Safety Information

[ Hazard Codes ]:
Xn:Harmful

[ Risk Phrases ]:
R21/22;R36

[ Safety Phrases ]:
S36/37-S36/37/39-S26

[ RIDADR ]:
UN 2811 6.1/PG 3

[ WGK Germany ]:
1

[ RTECS ]:
GV9100000

[ Packaging Group ]:
III

[ Hazard Class ]:
6.1

[ HS Code ]:
29061900

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • Cyclohexanone
  • Bromo(ethynyl)magnesium
  • 2-((1-ethynylcyclohexyl)oxy)tetrahydro-2H-pyran
  • Acetylene
  • (1-ethynylcyclohexyl) 4-nitrobenzoate
  • 1-(Trimethylsilylethynyl)cyclohexanol
  • Lithium (trimethylsilyl)acetylide
  • triethyl-(1-ethynylcyclohexyl)oxysilane
  • Calcium carbide
  • sodium acetylide

DownStream

  • Cyclohexane,(2-bromoethenylidene)-
  • (1-Cyclohexenyl)acetylene
  • Cyclohexanone
  • Ethanone,1-(1-cyclohexen-1-yl)-
  • Cyclohexanol,1-ethenyl-
  • 1-Hydroxy-α-methylcyclohexaneacetonitrile
  • Cyclohexene,1-(2-bromoethynyl)-
  • 1-(Trimethylsilylethynyl)cyclohexanol
  • 1-[2-[3-[tert-butyl(dimethyl)silyl]oxyphenyl]ethynyl]cyclohexan-1-ol
  • 1-Cyclohexylethan-1-one

Customs

[ HS Code ]: 2906199090

[ Summary ]:
2906199090. cyclanic, cyclenic or cyclotherpenic alcohols. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:5.5%. General tariff:30.0%

Related Compounds

  • 1-Ethynyl-1-cyclohexanol
  • 1-ethynyl-1-(propan-2-yl)cyclopropane
  • 1-ethynyl-1-chloro-4-methyl-cyclohexane
  • 1-ethynyl-1,5-dimethyl-4-oxohexyl acetate
  • 1-ethynyl-1-cycloheptene
  • 1-Ethynyl-1-(triisopropylsilyloxy)cyclopropane
  • N-(2,4-difluorophenyl)-2-(2-(4-methoxyphenyl)-4-oxo-3,4-dihydrobenzo[b][1,4]thiazepin-5(2H)-yl)acetamide
  • N-(2,4-difluorophenyl)-2-(2-(3,4-dimethoxyphenyl)-4-oxo-3,4-dihydrobenzo[b][1,4]thiazepin-5(2H)-yl)acetamide
  • N-(2,3-dimethylphenyl)-2-(2-(furan-2-yl)-4-oxo-3,4-dihydrobenzo[b][1,4]thiazepin-5(2H)-yl)acetamide
  • N-(4-butylphenyl)-2-(2-(furan-2-yl)-4-oxo-3,4-dihydrobenzo[b][1,4]thiazepin-5(2H)-yl)acetamide
  • N-(2,4-dimethoxyphenyl)-2-(2-(furan-2-yl)-4-oxo-3,4-dihydrobenzo[b][1,4]thiazepin-5(2H)-yl)acetamide
  • 2-(2-(furan-2-yl)-4-oxo-3,4-dihydrobenzo[b][1,4]thiazepin-5(2H)-yl)-N-(2-(trifluoromethyl)phenyl)acetamide
  • N-cyclopentyl-2-(2-(furan-2-yl)-4-oxo-3,4-dihydrobenzo[b][1,4]thiazepin-5(2H)-yl)acetamide
  • 5-(3-fluorobenzyl)-2-(furan-2-yl)-2,3-dihydrobenzo[b][1,4]thiazepin-4(5H)-one
  • 5-(4-fluorobenzyl)-2-(furan-2-yl)-2,3-dihydrobenzo[b][1,4]thiazepin-4(5H)-one
  • 2-(furan-2-yl)-5-(2-oxo-2-phenylethyl)-2,3-dihydrobenzo[b][1,4]thiazepin-4(5H)-one
The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.