1-Bromo-2-methylpropane

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Names

[ CAS No. ]:
78-77-3

[ Name ]:
1-Bromo-2-methylpropane

[Synonym ]:
1-Bromo-2-methylpropane
EINECS 201-141-2
1-Bromo-2-methyl propane
Propane, 1-bromo-2-methyl-
MFCD00000217

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
90.7±8.0 °C at 760 mmHg

[ Melting Point ]:
-119 °C

[ Molecular Formula ]:
C4H9Br

[ Molecular Weight ]:
137.018

[ Flash Point ]:
18.3±0.0 °C

[ Exact Mass ]:
135.988754

[ LogP ]:
2.56

[ Vapour Pressure ]:
62.9±0.2 mmHg at 25°C

[ Index of Refraction ]:
1.436

[ Water Solubility ]:
0.51 g/L (18 ºC)

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
TX4140000
CHEMICAL NAME :
Propane, 1-bromo-2-methyl-
CAS REGISTRY NUMBER :
78-77-3
LAST UPDATED :
199709
DATA ITEMS CITED :
5
MOLECULAR FORMULA :
C4-H9-Br
MOLECULAR WEIGHT :
137.04
WISWESSER LINE NOTATION :
E1Y1&1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
1660 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI Volume(issue)/page/year: 20(12),52,1976
TYPE OF TEST :
LC50 - Lethal concentration, 50 percent kill
ROUTE OF EXPOSURE :
Inhalation
SPECIES OBSERVED :
Mammal - species unspecified
DOSE/DURATION :
50500 mg/m3
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI Volume(issue)/page/year: 18(4),55,1974 ** TUMORIGENIC DATA **
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
3000 mg/kg/8W-I
TOXIC EFFECTS :
Tumorigenic - neoplastic by RTECS criteria Lungs, Thorax, or Respiration - tumors
REFERENCE :
CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year: 35,1411,1975

Safety Information

[ Symbol ]:

GHS02, GHS07

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H225-H315-H319-H335

[ Precautionary Statements ]:
P210-P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
F:Flammable

[ Risk Phrases ]:
R11;R36/37/38

[ Safety Phrases ]:
S16-S23-S37/39-S26

[ RIDADR ]:
UN 2342 3/PG 2

[ WGK Germany ]:
3

[ RTECS ]:
TX4140000

[ Packaging Group ]:
II

[ Hazard Class ]:
3

[ HS Code ]:
2903299090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • isobutanol
  • Isobutane Residual Solvent Standard
  • Isobutylene
  • n-Butane
  • 2-isobutoxy-4-methyl-1,3,2-dioxaborinane
  • triisobutyl antimony (2+), dibromide
  • 1-Iodo-2-methylpropane
  • Isobutyl chloride
  • triisobutylborane

DownStream

  • 4-Isobutoxybenzoic acid
  • Isobutyl nitrite
  • 2-METHYL-1-NITROPROPANE
  • 2-Isobutylthiophene
  • 4-methylpentanenitrile
  • 5-(TERT-BUTYL)FURAN-2-CARBOXYLIC ACID
  • Isoamyl ether
  • Dimethyl isobutylmalonate
  • 2-Isobutoxyethanol
  • Isobutanethiol

Customs

[ HS Code ]: 2903399090

[ Summary ]:
2903399090. brominated,fluorinated or iodinated derivatives of acyclic hydrocarbons. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:5.5%. General tariff:30.0%

Articles

Efficient synthesis of 1-alkyl (aralkyl)-3-methyl (ethyl) imidazolium halides: precursors for room-temperature ionic liquids Dzyuba SV and Bartsch RA

J. Heterocycl. Chem. 38(1)265-268 , 265-268, (2001)


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