2-Chlorobutane

Suppliers

Names

[ CAS No. ]:
78-86-4

[ Name ]:
2-Chlorobutane

[Synonym ]:
Butane, 2-chloro-
2-Butylchloride
sec.-butyl chloride
(2RS)-chlorobutane
(±)-2-Chlorobutane
2-chloro-butane
2-Chlorobutane
Butane,2-chloro
MFCD00000871
GY2&1
sec-Butyl chloride
sec-C4H9Cl
s-butyl chloride
2-chloro-butan
2-Chlorbutan
EINECS 201-151-7

Chemical & Physical Properties

[ Density]:
0.9±0.1 g/cm3

[ Boiling Point ]:
69.2±8.0 °C at 760 mmHg

[ Melting Point ]:
-140 °C

[ Molecular Formula ]:
C4H9Cl

[ Molecular Weight ]:
92.567

[ Flash Point ]:
-15.0±0.0 °C

[ Exact Mass ]:
92.039276

[ LogP ]:
2.38

[ Vapour Pressure ]:
146.9±0.1 mmHg at 25°C

[ Index of Refraction ]:
1.393

[ Stability ]:
Stable. Flammable - note low flash point. May form explosive mixtures with air. Incompatible with strong oxidizing agents.

[ Water Solubility ]:
immiscible

MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
EJ6475000
CHEMICAL NAME :
Butane, 2-chloro-
CAS REGISTRY NUMBER :
78-86-4
BEILSTEIN REFERENCE NO. :
1718770
LAST UPDATED :
199709
DATA ITEMS CITED :
6
MOLECULAR FORMULA :
C4-H9-Cl
MOLECULAR WEIGHT :
92.58
WISWESSER LINE NOTATION :
GY2&1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
20 mL/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
AIHAAP American Industrial Hygiene Association Journal. (AIHA, 475 Wolf Ledges Pkwy., Akron, OH 44311) V.19- 1958- Volume(issue)/page/year: 30,470,1969
TYPE OF TEST :
LCLo - Lowest published lethal concentration
ROUTE OF EXPOSURE :
Inhalation
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
8000 ppm/4H
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
AIHAAP American Industrial Hygiene Association Journal. (AIHA, 475 Wolf Ledges Pkwy., Akron, OH 44311) V.19- 1958- Volume(issue)/page/year: 30,470,1969
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
20 mL/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
AIHAAP American Industrial Hygiene Association Journal. (AIHA, 475 Wolf Ledges Pkwy., Akron, OH 44311) V.19- 1958- Volume(issue)/page/year: 30,470,1969 ** TUMORIGENIC DATA **
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
3240 mg/kg/8W-I
TOXIC EFFECTS :
Tumorigenic - neoplastic by RTECS criteria Lungs, Thorax, or Respiration - tumors
REFERENCE :
CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year: 35,1411,1975

Safety Information

[ Symbol ]:

GHS02

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H225

[ Precautionary Statements ]:
P210

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
F:Flammable;

[ Risk Phrases ]:
R11

[ Safety Phrases ]:
S16-S29-S7/9-S9

[ RIDADR ]:
UN 1127 3/PG 2

[ WGK Germany ]:
2

[ RTECS ]:
EJ6475000

[ Packaging Group ]:
II

[ Hazard Class ]:
3

[ HS Code ]:
29031980

Synthetic Route

Precursor & DownStream

Precursor

  • (±)-2-Butanol
  • SEC-BUTYLACETATE
  • Trimethyl(1-methylpropoxy)silane
  • P-TOLUENESULFONIC ACID SEC-BUTYL ESTER
  • Butanol
  • n-Butane
  • 2-Bromobutane
  • nonafluoro-tert-butanesulfenyl chloride
  • 1-Butene
  • n-butyl 2-chloro-1,1,2-trifluoroethyl ether

DownStream

  • (S)-(+)-2-Butanol
  • (R)-(-)-2-Butanol
  • HYDROGEN CYANIDE
  • Cyanogen chloride
  • 3-Methylhexane
  • 3,4-Dimethylhexane
  • Decane
  • 3-Methyloctane

Customs

[ HS Code ]: 29031980


Related Compounds

  • (R)-2-chlorobutane
  • (S)-2-chlorobutane
  • 1-bromo-2-chlorobutane
  • (+/-)-2-chlorobutane-d9
  • Perfluoro-2-chlorobutane
  • (2R)-2-chlorobutane-1,4-diol
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-{3-[(Dimethylamino)methyl]phenyl}-2,2-difluoroethan-1-ol
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 1-[1-(4-Ethynylphenyl)cyclopropyl]cyclopropan-1-amine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • 5-(1-Amino-3-hydroxycyclobutyl)-2-methylphenol
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde