Amino-2-propanol
Suppliers
Names
[ CAS No. ]:
78-96-6
[ Name ]:
Amino-2-propanol
[Synonym ]:
2-Propanol,1-amino-
2-Hydroxypropanamine
(RS)-1-Amino-2-hydroxypropane
1-Amino-2-hydroxypropane
Isopropanolamine
propan-2-ol, 1-amino-
(±)-1-Amino-2-propanol
1-Aminopropan-2-ol
(RS)-1-amino-2-propanol
2-Propanol, 1-amino- (8CI,9CI)
UNII:UE40BY1BZW
2-Hydroxy-1-propylamine
2-Propanol, 1-amino-
MFCD00008139
(±)-Isopropanolamine
1-Amino-2-propanol
EINECS 201-162-7
2-Propanol, 1-amino-, (±)-
Amino-2-propanol
Chemical & Physical Properties
[ Density]:
0.9±0.1 g/cm3
[ Boiling Point ]:
159.9±13.0 °C at 760 mmHg
[ Melting Point ]:
-2ºC
[ Molecular Formula ]:
C3H9NO
[ Molecular Weight ]:
75.110
[ Flash Point ]:
73.9±0.0 °C
[ Exact Mass ]:
75.068413
[ PSA ]:
46.25000
[ LogP ]:
-0.96
[ Vapour density ]:
2.6 (vs air)
[ Vapour Pressure ]:
0.9±0.6 mmHg at 25°C
[ Index of Refraction ]:
1.440
[ Stability ]:
Stable. Substances to be avoided include strong oxidizing agents. Combustible. Hygroscopic.
[ Water Solubility ]:
freely soluble
[ Freezing Point ]:
1.4℃
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- UA5775000
- CHEMICAL NAME :
- 2-Propanol, 1-amino-
- CAS REGISTRY NUMBER :
- 78-96-6
- BEILSTEIN REFERENCE NO. :
- 0605275
- LAST UPDATED :
- 199710
- DATA ITEMS CITED :
- 15
- MOLECULAR FORMULA :
- C3-H9-N-O
- MOLECULAR WEIGHT :
- 75.13
- WISWESSER LINE NOTATION :
- Z1YQ1
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- Open irritation test
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rabbit
- REFERENCE :
- UCDS** Union Carbide Data Sheet. (Union Carbide Corp., 39 Old Ridgebury Rd., Danbury, CT 06817) Volume(issue)/page/year: 5/21/1971
- TYPE OF TEST :
- Standard Draize test
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rabbit
- REFERENCE :
- 85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986 Volume(issue)/page/year: -,683,1986
- TYPE OF TEST :
- Standard Draize test
- ROUTE OF EXPOSURE :
- Administration into the eye
- SPECIES OBSERVED :
- Rodent - rabbit
- REFERENCE :
- UCDS** Union Carbide Data Sheet. (Union Carbide Corp., 39 Old Ridgebury Rd., Danbury, CT 06817) Volume(issue)/page/year: 5/21/1971
- TYPE OF TEST :
- Standard Draize test
- ROUTE OF EXPOSURE :
- Administration into the eye
- SPECIES OBSERVED :
- Rodent - rabbit
- REFERENCE :
- 85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986 Volume(issue)/page/year: -,683,1986 ** ACUTE TOXICITY DATA **
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 1715 mg/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity) Gastrointestinal - hypermotility, diarrhea Nutritional and Gross Metabolic - body temperature decrease
- REFERENCE :
- GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI Volume(issue)/page/year: 30(7),46,1986
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 250 mg/kg
- TOXIC EFFECTS :
- Behavioral - excitement
- REFERENCE :
- CBCCT* "Summary Tables of Biological Tests," National Research Council Chemical-Biological Coordination Center. (National Academy of Science Library, 2101 Constitution Ave., NW, Washington, DC 20418) Volume(issue)/page/year: 4,232,1952
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 1640 uL/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- UCDS** Union Carbide Data Sheet. (Union Carbide Corp., 39 Old Ridgebury Rd., Danbury, CT 06817) Volume(issue)/page/year: 5/21/1971
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Mammal - species unspecified
- DOSE/DURATION :
- >1 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI Volume(issue)/page/year: 30(7),46,1986 ** REPRODUCTIVE DATA **
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Unreported
- DOSE :
- 280 ug/kg
- SEX/DURATION :
- male 1 day(s) pre-mating
- TOXIC EFFECTS :
- Reproductive - Fertility - pre-implantation mortality (e.g. reduction in number of implants per female; total number of implants per corpora lutea)
- REFERENCE :
- TLSMA6 Trudy Leningradskogo Sanitarno-Gigienicheskogo Meditsinskogo Instituta. (Leningrad, Russia) V.1-145, 1949-82. Discontinued. Volume(issue)/page/year: 140,79,1981 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-RUSSIA:STEL 1 mg/m3;Skin JAN 1993 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 83332 No. of Facilities: 3204 (estimated) No. of Industries: 60 No. of Occupations: 59 No. of Employees: 51002 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 83332 No. of Facilities: 6922 (estimated) No. of Industries: 79 No. of Occupations: 80 No. of Employees: 132873 (estimated) No. of Female Employees: 13538 (estimated)
Safety Information
[ Symbol ]:
GHS05, GHS07
[ Signal Word ]:
Danger
[ Hazard Statements ]:
H302 + H312-H314
[ Precautionary Statements ]:
P280-P305 + P351 + P338-P310
[ Personal Protective Equipment ]:
Faceshields;full-face respirator (US);Gloves;Goggles;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
[ Hazard Codes ]:
C:Corrosive
[ Risk Phrases ]:
R34
[ Safety Phrases ]:
S23-S26-S36-S45
[ RIDADR ]:
UN 2735
[ WGK Germany ]:
1
[ RTECS ]:
UA5775000
[ Packaging Group ]:
II
[ Hazard Class ]:
8.0
[ HS Code ]:
2922199090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2922199090
[ Summary ]:
2922199090. other amino-alcohols, other than those containing more than one kind of oxygen function, their ethers and esters; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%
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