6-O-Methyl Guanosine

Suppliers

Names

[ CAS No. ]:
7803-88-5

[ Name ]:
6-O-Methyl Guanosine

[Synonym ]:
9H-Purin-2-amine, 6-methoxy-9-β-D-ribofuranosyl-
6-O-METHYLGUANOSINE
Guanosine,o-methyl
2-amino-6-methoxypurine riboside
6-Methoxy-6-deoxoguanosine
o-methoxydeoxyguanosine
O-Methylguanosine
6-Methoxy-9-(β-D-ribofuranosyl)-9H-purin-2-amine
O6-METHYLGUANOSINE
o-methyl-guanosin
2-Amino-6-methoxypurine Ribonucleoside

Chemical & Physical Properties

[ Density]:
2.0±0.1 g/cm3

[ Boiling Point ]:
721.0±70.0 °C at 760 mmHg

[ Molecular Formula ]:
C11H15N5O5

[ Molecular Weight ]:
297.267

[ Flash Point ]:
389.9±35.7 °C

[ Exact Mass ]:
297.107330

[ PSA ]:
148.77000

[ LogP ]:
-0.58

[ Vapour Pressure ]:
0.0±2.4 mmHg at 25°C

[ Index of Refraction ]:
1.829

[ Storage condition ]:
2-8℃

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
MF8790000
CHEMICAL NAME :
Guanosine, O-methyl-
CAS REGISTRY NUMBER :
7803-88-5
LAST UPDATED :
199612
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C11-H15-N5-O5
MOLECULAR WEIGHT :
297.31
WISWESSER LINE NOTATION :
T56 BN DN FVN INJ HZ B- BT5OTJ CO1 DQ E1Q

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

TYPE OF TEST :
DNA damage
TEST SYSTEM :
Rodent - hamster Lung
DOSE/DURATION :
2400 nmol/L
REFERENCE :
ENMUDM Environmental Mutagenesis. (New York, NY) V.1-9, 1979-87. For publisher information, see EMMUEG. Volume(issue)/page/year: 4,321,1982

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • Methanol
  • 6-Chloroguanineriboside
  • 3',5'-di-O-acetyl-2'-deoxy-2-N-(mono-p-methoxytrityl)guanosine
  • N,N,N-Trimethylanilinium hydroxide
  • Guanosine
  • b-D-Ribofuranose 1-acetate 2,3,5-tribenzoate
  • 2-Amino-6-chloropurine
  • 6-O-Methylguanine
  • Trimethylsulfonium hydroxide

DownStream

  • O(6),7-dimethylguanine
  • 4-methoxy-3H-imidazo[2,1-b]purine

Related Compounds

  • 6-O-methyl guanosine-5'-monophosphate
  • 2'-C-methyl-6-O-methyl-guanosine
  • (2'R)-2'-Deoxy-2'-fluoro-2'-Methyl-6-O-Methyl-guanosine
  • 6-O-Methyl-1-O,2-O,3-O,4-O-tetrakis(trimethylsilyl)-β-D-glucopyranose
  • 6-O-Methyl-2',4''-bis-O-(trimethylsilyl)erythromycin 9-[O-(1-ethoxy-1-methylethyl)oxime]
  • 6-O-(methyl 5-acetamido-3,5-dideoxy-α-D-glycero-D-galacto-2-nonulopyranosylonate)-D-galactose