1-(4-(p-Nitrophenyl)-2-thiazolyl)hydantoin

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Names

[ CAS No. ]:
78140-08-6

[ Name ]:
1-(4-(p-Nitrophenyl)-2-thiazolyl)hydantoin

Chemical & Physical Properties

[ Density]:
1.578g/cm3

[ Molecular Formula ]:
C12H8N4O4S

[ Molecular Weight ]:
304.28100

[ Exact Mass ]:
304.02700

[ PSA ]:
139.85000

[ LogP ]:
2.63860

[ Index of Refraction ]:
1.682

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
MU3930000
CHEMICAL NAME :
Hydantoin, 1-(4-(p-nitrophenyl)-2-thiazolyl)-
CAS REGISTRY NUMBER :
78140-08-6
LAST UPDATED :
199612
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C12-H8-N4-O4-S
MOLECULAR WEIGHT :
304.30
WISWESSER LINE NOTATION :
T5NVMV EHJ A- BT5N CSJ ER DNW

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
681 mg/kg
TOXIC EFFECTS :
Behavioral - changes in motor activity (specific assay) Behavioral - muscle weakness Biochemical - Metabolism (Intermediary) - effect on inflammation or mediation of inflammation
REFERENCE :
PHARAT Pharmazie. (VEB Verlag Volk und Gesundheit, Neue Gruenstr. 18, Berlin DDR-1020, Ger. Dem. Rep.) V.1- 1946- Volume(issue)/page/year: 38,341,1983

Safety Information

[ HS Code ]:
2934999090

Synthetic Route

Customs

[ HS Code ]: 2934999090

[ Summary ]:
2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%


Related Compounds

  • 1-(4-(p-Ethylphenyl)-2-thiazolyl)hydantoin
  • 1-(4-(p-Chlorophenyl)-2-thiazolyl)hydantoin
  • 1-(4-(2-Bromo-4-nitrophenyl)-2-thiazolyl)hydantoin
  • [4-(p-Nitrophenyl)-2-thiazolyl]thiourea
  • 1-(4-Ethyl-2-thiazolyl)hydantoin
  • 1-(4-nitrophenyl)-2-propyl tosylate