CDPPB

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Names

[ CAS No. ]:
781652-57-1

[ Name ]:
CDPPB

[Synonym ]:
mGluR5 Ligand,CDPPB
CDPPB

Chemical & Physical Properties

[ Density]:
1.203g/cm3

[ Boiling Point ]:
523.277ºC at 760 mmHg

[ Molecular Formula ]:
C23H16N4O

[ Molecular Weight ]:
364.39900

[ Flash Point ]:
270.268ºC

[ Exact Mass ]:
364.13200

[ PSA ]:
70.71000

[ LogP ]:
4.73628

[ Index of Refraction ]:
1.655

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302

[ Hazard Codes ]:
Xi

[ RIDADR ]:
NONH for all modes of transport

Articles

Enhancement of extinction learning attenuates ethanol-seeking behavior and alters plasticity in the prefrontal cortex.

J. Neurosci. 34(22) , 7562-74, (2014)

Addiction is a chronic relapsing disorder in which relapse is often initiated by exposure to drug-related cues. The present study examined the effects of mGluR5 activation on extinction of ethanol-cue...

The mGluR5 positive allosteric modulator, CDPPB, ameliorates pathology and phenotypic signs of a mouse model of Huntington's disease.

Neurobiol. Dis. 73 , 163-73, (2014)

Huntington's disease (HD) is an autosomal-dominant neurodegenerative disorder caused by a polyglutamine expansion in the amino-terminal region of the huntingtin protein (htt), leading to motor dysfunc...

Therapeutic effects of metabotropic glutamate receptor 5 positive allosteric modulator CDPPB on phencyclidine-induced cognitive deficits in mice.

Fundam. Clin. Pharmacol. 27(5) , 483-8, (2013)

This study was undertaken to examine the effects of CDPPB (3-cyano-N-(1,3-diphenyl-1H-pyrazol-5-yl)benzamide), a positive allosteric modulator (PAM) of metabotropic glutamate receptor 5 (mGlu₅), on co...


More Articles

Related Compounds

  • N-benzhydryl-4-(2-(thiophene-2-carboxamido)ethyl)piperazine-1-carboxamide
  • N-isopropyl-4-(2-(thiophene-2-carboxamido)ethyl)piperazine-1-carboxamide
  • N-(tert-butyl)-4-(2-(thiophene-3-carboxamido)ethyl)piperazine-1-carboxamide
  • N-(3-methoxyphenyl)-4-(2-(thiophene-3-carboxamido)ethyl)piperazine-1-carboxamide
  • 1-[(3,4-Dimethoxyphenyl)methyl]-3-{2-[4-(thiophene-2-carbonyl)piperazin-1-yl]ethyl}urea
  • 1-(4-Methoxybenzyl)-3-(2-(4-(methylsulfonyl)piperazin-1-yl)ethyl)urea
  • 1-Benzhydryl-3-(2-(4-(methylsulfonyl)piperazin-1-yl)ethyl)urea
  • 1-(5-Chloro-2-methoxyphenyl)-3-(2-(4-(methylsulfonyl)piperazin-1-yl)ethyl)urea
  • N1-(thiophen-2-ylmethyl)-N4-(2,2,2-trifluoroethyl)piperidine-1,4-dicarboxamide
  • N1-(2-methoxyethyl)-N4-(2,2,2-trifluoroethyl)piperidine-1,4-dicarboxamide
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