1-Benzyl 5-methyl N,N-bis{[(2-methyl-2-propanyl)oxy]carbonyl}-D-g lutamate

Names

[ CAS No. ]:
784156-32-7

[ Name ]:
1-Benzyl 5-methyl N,N-bis{[(2-methyl-2-propanyl)oxy]carbonyl}-D-g lutamate

[Synonym ]:
1-benzyl 3-methyl 6-methoxyindole-1,3-dicarboxylate
1-Benzyl 3-Methyl 6-Methoxy-1H-indole-1,3-dicarboxylate

Chemical & Physical Properties

[ Density]:
1.153g/cm3

[ Boiling Point ]:
514ºC at 760 mmHg

[ Molecular Formula ]:
C23H33NO8

[ Molecular Weight ]:
451.51000

[ Flash Point ]:
264.7ºC

[ Exact Mass ]:
451.22100

[ PSA ]:
108.44000

[ LogP ]:
4.22380

[ Index of Refraction ]:
1.504

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • Di-tert-butyl dicarbonate
  • Boc-D-glutamic acid α-benzylester
  • (Trimethylsilyl)diazomethane
  • (S)-benzyl 5-amino-2-(tert-butoxycarbonylamino)-5-oxopentanoate
  • 1-Benzyl 5-methyl N-{[(2-methyl-2-propanyl)oxy]carbonyl}-D-glutam ate

DownStream

  • [(3R,6S)-6-(2,3-difluorophenyl)-2-oxoazepan-3-yl]carbamate
  • (3R,6S)-3-amino-6-(2,3-difluorophenyl)-1-(2,2,2-trifluoroethyl)azepan-2-one
  • Benzyl (2R,5E)-2-(bis{[(2-methyl-2-propanyl)oxy]carbonyl}amino)-6 -nitro-5-hexenoate
  • Benzyl N,N-bis{[(2-methyl-2-propanyl)oxy]carbonyl}-5-oxo-D-norval inate
  • (5S)-5-(2,3-Difluorophenyl)-N2,N2-bis{[(2-methyl-2-propanyl)oxy]carbonyl}-D-lysine
  • Benzyl (5S)-5-(2,3-difluorophenyl)-N,N-bis{[(2-methyl-2-propanyl) oxy]carbonyl}-6-nitro-D-norleucinate