Trequinsin hydrochloride

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Names

[ CAS No. ]:
78416-81-6

[ Name ]:
Trequinsin hydrochloride

[Synonym ]:
trequinsine
HL 725 HCL
TREQUINSIN HYDROCHLORIDE MINIMUM
TREQUINSIN HYDROCHLORIDE
Trequinsin,HCl
HL 725

Chemical & Physical Properties

[ Boiling Point ]:
613.8ºC at 760 mmHg

[ Molecular Formula ]:
C24H28ClN3O3

[ Molecular Weight ]:
441.95000

[ Flash Point ]:
325ºC

[ Exact Mass ]:
441.18200

[ PSA ]:
57.75000

[ LogP ]:
4.38670

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
UW7727000
CHEMICAL NAME :
4H-Pyrimido(6,1-a)isoquinolin-4-one, 2,3,6,7-tetrahydro-9,10-dimethoxy-3-methyl- 2-((2,4,6-trimethylphenyl)imino)-, monohydrochloride
CAS REGISTRY NUMBER :
78416-81-6
LAST UPDATED :
198803
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C24-H27-N3-O3.Cl-H
MOLECULAR WEIGHT :
442.00

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
150 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 27,1470,1984

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xi

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ RTECS ]:
UW7727000

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 4-nitrophenyl decanoyl-L-phenylalaninate
  • 4H-Pyrimido(6,1-a)isoquinolin-4-one, 6,7-dihydro-9,10-dimethoxy-2-((2, 4,6-trimethylphenyl)amino)-, hydrochloride, hydrate (1:1:2)
  • methyl iodide

DownStream

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Related Compounds

  • Trequinsin hydrochloride
  • Tyrocidine, hydrochloride
  • Triprolidine hydrochloride
  • Minoxidil hydrochloride
  • Elacridar hydrochloride
  • dodecylamine hydrochloride
  • 2-(2-bromo-4-methoxyphenyl)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)acetic acid
  • 2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-2-(3-iodo-1-methyl-1H-pyrazol-4-yl)acetic acid
  • Methyl 8-methyl-1,7-dioxa-4-azaspiro[4.4]nonane-3-carboxylate
  • Ethyl 8-benzyl-1-oxa-4,8-diazaspiro[4.5]decane-3-carboxylate
  • 4-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)naphthalene-2-carboxylic acid
  • Ethyl 5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazine-6-carboxylate
  • 1-{7'-Amino-6',7'-dihydrospiro[azetidine-3,5'-pyrrolo[1,2-a]imidazole]-1-yl}ethan-1-one
  • 1-[(2,3-Dihydro-1,4-benzodioxin-2-yl)methyl]cyclopropane-1-carboxylic acid
  • 4-({[(Tert-butoxy)carbonyl]amino}methyl)-2,6-dimethylbenzoic acid
  • 3-(2,3-Dihydro-1,4-benzodioxin-2-yl)-2,2-dimethylpropan-1-amine
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